1例不明原因新型冠状病毒肺炎及其密切接触者调查分析  

Investigation of a COVID-19 case with unknown cause and its close contacts

作　　者：刘仲[1] 赵梦娇[1] 杨国樑[1] 赵怀龙[1] 王琳琳 常彩云[1] 耿兴义[1] LIU Zhong;ZHAO Mengjiao;YANG Guoliang;ZHAO Huailong;WANG Linlin;CHANG Caiyun;GENG Xingyi(Emergency Response Group,Jinan Municipal Center for Disease Control and Prevention,Jinan 250021,Shandong,China;Department of Infectious Disease Control,Center for Disease Control and Prevention of Shizhong District,Jinan 250000,Shandong,China)

机构地区：[1]济南市疾病预防控制中心应急处置组,山东济南250021 [2]济南市市中区疾病预防控制中心传染病防治科,山东济南250000

出　　处：《山东大学学报（医学版）》2020年第4期49-53,共5页Journal of Shandong University:Health Sciences

摘　　要：目的回顾性分析济南市1例感染原因不明的新型冠状病毒肺炎病例引起的家庭聚集性疫情。方法应用现场流行病学方法调查1例新型冠状病毒肺炎病例及其2例2代病例,并对29名密切接触者实施医学隔离观察,采用RT-PCR对采集的相关标本进行新型冠状病毒肺炎病毒核酸检测。结果3例新型冠状病毒肺炎确诊病例为家庭聚集性病例。首发病例(病例A)发病前有短期外出史,感染来源不明确。病例B、C因与病例A共同生活被传染。接触时间短、接触频率较低、有一定防护措施的密切接触者经核酸检测、医学观察,均未出现异常。结论新型冠状病毒的传播力强,应该把早期发现和早期隔离筛查密切接触者作为防控重点。Objective To retrospectively analyze a family cluster of coronavirus disease 2019(COVID-19)with unknown cause in Jinan City.Methods One case of COVID-19 and two second-generation cases were investigated using field epidemiological methods,and 29 close contacts were quarantined.All cases received nucleic acid test with RT-PCR.Results All three cases were family clusters.The initial case(case A)had a short history of travel before onset,but the source of infection was unclear.Cases B and C lived with case A and were infected.Other close contacts with short contact time,low contact frequency and protective measures showed no abnormalities and were tested negative.Conclusion As 2019-nCoV is highly infectious,early detection and early screening of close contacts should be the focus of prevention and control.

关 键 词：新型冠状病毒肺炎 聚集性 流行病学调查 密切接触者 

分 类 号：R181.3[医药卫生—流行病学]