不同加工方法对骨碎补质量影响研究  

Study on the Effect of Different Processing on the Quality of Drynaria fortunei

作　　者：杨润 王亮 谢宇 罗君 薛鑫宇 张丽艳 Yang Run;Wang Liang;Xie Yu;Luo Jun;Xue Xinyu;Zhang Liyan(Guiyang Collage of Traditional Chinese Medicine,Guiyang 550025,China;Guizhou Guangjitang Pharmaceutical Company Limited,Guiyang 550014,China;First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine(TCM),Guiyang 550001,China)

机构地区：[1]贵州中医药大学,贵州贵阳550025 [2]贵州广济堂药业有限公司,贵州贵阳550014 [3]贵州中医药大学第一附属医院,贵州贵阳550001

出　　处：《亚太传统医药》2020年第3期55-59,共5页Asia-Pacific Traditional Medicine

基　　金：贵州省国内一流建设学科(中药学)(GNYL[2017]008号);贵州省科技支撑计划项目(黔科合支撑[2018]2772);贵州省科技厅贵阳中医学院第一附属医院联合基金(黔科合LH字[2015]7801);国家中医药管理局中药特色技术传承人才项目(国中医药办人教函[2018]204号);贵阳国家高新技术产业开发区管理委员会科技型中小企业技术创新基金(GXCX2015-012)。

摘　　要：目的:通过测定不同加工方法对骨碎补水分、灰分、浸出物、柚皮苷含量的影响,为骨碎补的质量控制提供依据。方法:将10个产地的骨碎补生品及炮制品,去毛加工后,并将其分为4组,参照2015版《中国药典》四部通则和一部相关方法,对骨碎补水分、灰分、醇溶性浸出物及柚皮苷含量进行测定。结果:10个产地的骨碎补按照4个分组测量的结果:未去毛生品水分为12.09%~12.77%,总灰分为5.09%~7.38%,醇溶性浸出物为16.85%~26.65%,柚皮苷为7.246%~13.503%;去毛生品水分为5.93%~12.43%,总灰分为5.36%~7.18%,醇溶性浸出物为18.91%~28.73%,柚皮苷为6.788%~13.797%;未去毛炮制品水分为4.36%~6.52%,总灰分为6.18%~7.72%,醇溶性浸出物为17.51%~24.26%,柚皮苷为5.436%~9.689%;去毛炮制品水分为5.13%~9.44%,总灰分为5.22%~7.35%,醇溶性浸出物为21.84%~29.02%,柚皮苷为8.158%~15.142%。结论:骨碎补经去毛净制后,生品和炮制品的质量相对提高,为其质量控制提供了参考依据。Objective:To determine the effects of different processing methods on the moisture content,ash content,extract and naringin content of Drynaria fortunei,and to provide a basis for the quality control of Drynaria fortunei.Methods:Raw and processed bone crushing and filling products from 10 producing areas were deroughed and divided into four groups.The contents of bone crushing and filling water,ash content,alcohol-soluble extract and naringin content were determined by referring to the four general principles of Chinese pharmacopoeia 2015 and one related method.Results:The water content of raw products without hair removal was 12.09%~12.77%,the total ash content was 5.09%~7.38%,the alcohol-soluble extract was 16.85%~26.65%,and the content of taringin was 7.246%~13.503%.The moisture content of dehairy raw products was 5.93%~12.43%,the total ash content was 5.36%~7.18%,the alcohol-soluble extracts were 18.91%~28.73%,and the naringin content was 6.788%~13.797%.The water content of undehazed processed products was 4.36%~6.52%,the total ash content was 6.18%~7.72%,the alcohol soluble extracts were 17.51%~24.26%,and the naringin content was 5.436%~9.689%.The moisture content of hair removal products was 5.13%~9.44%,the total ash content was 5.22%~7.35%,the alcohol-soluble extracts were 21.84%~29.02%,and the content of ninglinin was 8.158%~15.142%.Conclusion:The quality of raw and processed products has been improved after the preparation of guxiaobijing,which provides reference for quality control.

关 键 词：骨碎补 柚皮苷 水分 灰分 醇溶性浸出物 含量测定 

分 类 号：R283[医药卫生—中药学]