复方泛影葡胺灌肠治疗经腹会阴直肠切除术后炎性肠梗阻的临床疗效分析  

Enema with gastrografin in treatment of inflammatory intestinal obstruction after transabdominal perineorectal resection

作　　者：杨鹏 孙诗俊 赵美兰[1] Yang Peng;Sun Shijun;Zhao Meilan(Department of Pharmacy,1Xinhua Hospital,Dalian University,Dalian 116021,China;Department of Pharmacy,2Jinzhou First People’s Hostital,Dalian 116100,China)

机构地区：[1]大连大学附属新华医院药剂科,116021 [2]大连市金州区第一人民医院药剂科,116100

出　　处：《国际医药卫生导报》2020年第10期1400-1402,共3页International Medicine and Health Guidance News

摘　　要：目的探讨复方泛影葡胺灌肠治疗经腹会阴直肠切除术后炎性肠梗阻的临床疗效。方法选取2014年1月至2018年12月于大连大学附属新华医院收治的60例经腹会阴直肠切除术后炎性肠梗阻患者,按随机数字表法分为两组,各30例。两组均行一次性吸痰管经造口置入术,其中研究组选用复方泛影葡胺灌肠治疗,而对照组选用传统温皂水灌肠治疗,比较分析两组患者的临床主症的变化、腹部体征变化及影像学变化。结果两组患者接受非手术治疗后均成功痊愈;研究组腹痛/腹胀缓解时间、首次排气/排便时间、解除肠梗阻/临床治愈时间、影像学上消除肠管高度扩张/气液平面时间分别为(3.67±2.02)h、(2.20±1.86)h、(35.00±11.25)h、(32.93±11.20)h,均低于对照组(15.23±11.32)h、(11.47±7.56)h、(61.40±9.72)h、(58.60±9.48)h,差异均有统计学意义(均P<0.05);研究组临床疗效及预后显著优于对照组,差异均有统计学意义(均P<0.05);且两组无1例灌肠液不良反应。结论经腹会阴直肠切除术后炎性肠梗阻患者的复方泛影葡胺灌肠治疗,其操作方式安全且可行,临床疗效显著,值得临床推广应用。Objective To investigate the clinical effect of enema with gastrografin in the treatment of inflammatory intestinal obstruction after transabdominal perineorectal resection.Methods A total of 60 patients with inflammatory intestinal obstruction after transabdominal perineorectal resection who received treatment in Xinhua Hospital from January,2016 to December,2018 were selected.These patients were randomly divided into a study group(n=30)and a control group(n=30)according to random number table.The two groups were performed catheterization of disposable sputum suction tube via stoma.Then the study group were given enema with gastrografin via disposable sputum suction tube,while the control group were given traditional soap water enema.Later,the two groups’changes of clinical primary symptoms and abdominal signs and iconography were compared and analyzed.Results The patients in both groups were successfully cured by non-surgical treatment.The relief time of abdominal pain and distension,the time of first exhaust and defecation,the time of relieving intestinal obstruction and clinical cure,and the time of eliminating highly expanded intestine and air fluid level in the study group were significantly shorter than those in the control group[(3.67±2.02)h vs.(15.23±11.32)h,(2.20±1.86)h vs.(11.47±7.56)h,(35.00±11.25)h vs.(61.40±9.72)h,and(32.93±11.20)h vs.(58.60±9.48)h;all P<0.05].what’s more,the clinical effect and prognosis in the study group were markedly better than those in the control group,and no adverse reactions caused by enema were noted in the two groups.Conclusion Enema with gastrografin in the treatment of inflammatory intestinal obstruction after transabdominal perineorectal resection is worthy of clinical application,because of it’s safety,feasibility,and significant clinical effects.

关 键 词：复方泛影葡胺 灌肠治疗 炎性肠梗阻 临床疗效 

分 类 号：R656[医药卫生—外科学]