益气解毒法防治PM2.5所致慢性气道炎症性疾病的理论探讨  

Theoretical study of tonifying qi and detoxication method on the prevention and treatment of PM2.5 induced chronic airway inflammatory disease

作　　者：吴雨潇 王智超 王振兴[1] 郭静[1] 肖玮[2] 王飞[1] WU Yu-xiao;WANG Zhi-chao;WANG Zhen-xing;GUO Jing;XIAO Wei;WANG Fei(School of Clinical Medicine,Chengdu University of TCM,Chengdu 610075,China;Affliliated Hospital of Chengdu University of TCM,Chengdu 610075,China)

机构地区：[1]成都中医药大学临床医学院,成都610075 [2]成都中医药大学附属医院,成都610075

出　　处：《中华中医药杂志》2020年第3期1152-1155,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：四川省学术和技术带头人培养支持经费(No.075005);成都市科技局技术创新研发项目(No.2018-YF05-00078-SN);成都中医药大学“杏林学者”科研基金(No.041030);成都中医药大学附属医院/四川省中医药科技发展基金(No.2017-D-YY-64)。

摘　　要：慢性气道炎症性疾病是由气道固有细胞、炎症细胞及多种细胞因子在内外界多因素刺激作用下参与的非特异性炎症性疾病。随着工业化程度提高,空气质量下降,空气中的PM2.5严重超标,持续刺激气道,造成慢性气道炎症性疾病发病率增多。中医药在防治哮喘、慢性阻塞性肺疾病等慢性气道炎症性疾病有明显的优势。文章以哮喘和慢阻肺为例,从中医“毒”邪角度来认识PM2.5,探讨PM2.5所致慢性气道炎症性疾病的病因病机学特点,并对益气解毒法进行阐述。深入探讨益气解毒法防治PM2.5所致的慢性气道炎症性疾病的实际意义。提出在防治PM2.5所致慢性气道炎症性疾病中运用益气解毒作为防治法则,以更好地指导临床运用。Chronic airway inflammatory disease is a non-specific inflammatory disease involving innate airway cells,inflammatory cells and a variety of cytokines stimulated by internal and external factors.With the improvement of industrialization and the decline of air quality,PM2.5 in the air seriously exceeded the standard and continuously stimulated the airway,resulting in an increase in the incidence of chronic airway inflammatory diseases.Traditional Chinese medicine has obvious advantages in the prevention and treatment of chronic airway inflammatory diseases such as asthma and chronic obstructive pulmonary disease(COPD).Taking asthma and COPD as examples,this paper explores the etiology and pathogenesis of chronic airway inflammation caused by PM2.5 from the perspective of‘toxic’evil of traditional Chinese medicine,and elaborates the method of tonifying qi and detoxication method.It also explores the practical significance of tonifying qi and detoxication method in the prevention and treatment of chronic airway inflammatory diseases caused by PM2.5.It is suggested that tonifying qi and detoxication method should be used as the prevention and treatment principle in the prevention and treatment of chronic airway inflammatory diseases caused by PM2.5,in order to better guide the clinical application.

关 键 词：益气解毒法 慢性气道炎症性疾病 PM2.5 中医 基础理论 

分 类 号：R259[医药卫生—中西医结合]