沙美特罗替卡松联合噻托溴铵吸入治疗中重度COPD的临床治疗效果观察  

Clinical Efficacy of Salmeterol-fluticasone Combined with Tiotropium Bromide Inhalation in the Treatment of Moderate to Severe COPD

作　　者：李晋[1] LI Jin(Dalian Central Hospital,Dalian 116033,China)

机构地区：[1]辽宁省大连市中心医院,辽宁大连116033

出　　处：《中国医药指南》2020年第13期124-125,共2页Guide of China Medicine

摘　　要：目的分析沙美特罗替卡松联合噻托溴铵吸入治疗中重度COPD的临床治疗效果。方法选择130例在我院住院治疗的中重度COPD患者,采用数字随机分组方法分为治疗组和对照组,对照组应用沙美特罗替卡松治疗,治疗组应用沙美特罗替卡松联合噻托溴铵吸入治疗,对比患者用药前后血气指标、肺功能相关指标和临床疗效。结果对比用药后两组患者PaCO2、PaO2以及6MWT、FEV1、FEV1%等指标水平治疗组均优于对照组;对比两组用药后临床总有效率治疗组高于对照组,P<0.05。结论中重度COPD应用沙美特罗替卡松联合噻托溴铵吸入治疗能够改善患者机体功能,帮助患者有效控制症状、病情、是效果显著的用药方案。Objective To analyze the clinical effect of salmeterol and tiotropium bromide inhalation in the treatment of moderate and severe COPD.Methods 130 patients with moderate to severe COPD in our hospital were randomly divided into treatment group and control group.The control group was treated with salmeterol-fluticasone,while the treatment group was treated with salmeterol-fluticasone combined with tiotropium bromide inhalation.The blood gas index,lung function related index and clinical efficacy were compared before and after the use of salmeterol-fluticasone combined with tiotropium bromide inhalation.Result The treatment group was superior to the control group in PaCO2,PaO20,6 MWT,FEV1,FEV1%and other indicators,and the total effective rate of the treatment group was higher than that of the control group(P<0.05).Conclusion Salmeterol and tiotropium bromide inhalation therapy for moderate to severe COPD can improve the body function of patients,help patients effectively control symptoms and conditions,and is an effective drug regimen.

关 键 词：COPD 中重度 沙美特罗替卡松 噻托溴铵 肺功能 

分 类 号：R563.1[医药卫生—呼吸系统]