探究血清降钙素原在终末期肾病合并细菌性脓毒症患者中的诊断价值  

To Explore the Diagnostic Value of Serum Procalcitonin in Patients with End-stage Nephropathy Complicated with Bacterial Sepsis

作　　者：徐长青[1] XU Chang-qing(Department of Laboratory,Tieling Central Hospital,Tieling 112001,China)

机构地区：[1]铁岭市中心医院检验科,辽宁铁岭112001

出　　处：《中国医药指南》2020年第13期170-171,共2页Guide of China Medicine

摘　　要：目的探讨分析血清降钙素原(PCT)在终末期肾病合并细菌性脓毒症患者中的诊断价值。方法回顾性分析2017年8月到2019年6月我院收治并确诊为终末期肾病的40例患者的临床资料,将患者按照是否合并细菌性脓毒症分为脓毒症A组和非脓毒症B组,每组各20例。对比两组肾病患者检测结果中的血清PCT、白细胞(WBC)、C-反应蛋白(CRP)、血肌酐(Scr)、表皮生长因子受体(eGFR)水平。结果脓毒症A组患者的血清PCT、WBC、CRP水平明显高于非脓毒症B组患者,差异具有统计学意义(P<0.05)。两组患者的Scr水平和eGFR水平,无统计学意义(P>0.05)。结论血清PCT对于终末期肾病合并细菌性脓毒症患者的诊断具有较高的参考意义,可以将血清PCT作为临床诊断的标志物。Objective To investigate the diagnostic value of serum procalcitonin(PCT)in patients with end-stage nephropathy complicated with bacterial sepsis.Methods The clinical data of 40 patients admitted to our hospital from August 2017 to June 2019 and diagnosed with end-stage nephropathy were retrospectively analyzed.The patients were divided into sepsis group A and non-sepsis group B according to whether bacterial sepsis was complicated or not,with 20 cases in each group.Serum levels of PCT,white blood cells(WBC),C-reactive protein(CRP),serum creatinine(Scr)and epidermal growth factor receptor(eGFR)were compared between the two groups.Results Serum PCT,WBC and CRP levels of patients in sepsis group A were significantly higher than those in non-sepsis group B,with statistically significant differences(P<0.05).Scr level and eGFR level in the two groups were not statistically significant(P>0.05).Conclusion Serum PCT has a high reference value in the diagnosis of end-stage renal disease with bacterial sepsis,and can be used as a clinical marker.

关 键 词：终末期肾病 降钙素原 细菌性脓毒症 诊断 表皮生长因子受体 C-反应蛋白 血肌酐 

分 类 号：R692[医药卫生—泌尿科学]