中西医结合疗法救治肝硬化合并肝性脑病的临床观察  

Clinical Observation on Treatment of Liver Cirrhosis Complicated with Hepatic Encephalopathy by Integrative Chinese and Western Medicine

作　　者：周伟 ZHOU Wei(Dalian Sixth People Hospital,Dalian 116001,China)

机构地区：[1]大连市第六人医院,辽宁大连116001

出　　处：《中国医药指南》2020年第13期190-191,共2页Guide of China Medicine

摘　　要：目的中西医结合疗法救治肝硬化合并肝性脑病的临床观察。方法选取我院2017年8月至2018年8月收治的56例肝硬化合并肝性脑病患者,随机分为观察组和对照组,每组28例。对照组行常规西医治疗,观察组行中西医结合疗法治疗。对比两组治疗有效率以及患者肝功能,其中肝功能以血氨和丙氨酸转氨酶的变化进行评定。结果观察组治疗有效率为92.86%(26/28)、对照组治疗有效率为78.57%(22/28)。两组差异具有统计学意义(P<0.05;χ^2=19.874)。观察组患者血氨水平治疗前为(162.3±28.6)μmol/L,治疗后为(51.7±11.4)μmol/L;丙氨酸转氨酶治疗治疗前为(201.8±23.4)U/L,治疗后为(70.8±10.6)U/L。对照组患者血氨水平治疗前为(161.7±29.3)μmol/L,治疗后为(78.5±12.6)μmol/L;丙氨酸转氨酶治疗治疗前为(198.4±26.1)U/L,治疗后为(91.2±11.3)U/L。两组治疗前肝功能指标差异无统计学意义(P>0.05;t=0.169、0.284),治疗后差异具有统计学意义(P<0.05;t=7.258、7.476)。结论中西医结合疗法救治肝硬化合并肝性脑病,有效率较高,患者肝功能改善明显,可予以临床推广。Objective To compare the treatment of cirrhosis with hepatic encephalopathy with integrated traditional Chinese and western medicine.Methods 56 patients with cirrhosis and hepatic encephalopathy admitted to our hospital from August 2008 to August 1818 were randomly divided into observation group and control group,28 cases in each group.The control group received routine Western medicine treatment,and the observation group was treated with integrated Chinese and Western medicine.The effective rate of treatment and the liver function of the patients were compared,and the liver function was evaluated by changes in blood ammonia and alanine aminotransferase.Results The effective rate of treatment in the observation group was 92.86%(26/28),and the effective rate in the control group was 78.57%(22/28).The difference between the two groups was statistically significant(P<0.05;χ^2=19.874).The blood ammonia level of the observation group was(162.3±28.6)μmol/L before treatment and(51.7±11.4)μmol/L after treatment;(201.8±23.4)U/L before treatment with alanine aminotransferase,after treatment(70.8±10.6)U/L.The blood ammonia level of the control group was(161.7±29.3)μmol/L before treatment and(78.5±12.6)μmol/L after treatment;(198.4±26.1)U/L before treatment with alanine aminotransferase,after treatment(91.2±11.3)U/L.There was no significant difference in liver function indexes between the two groups before treatment(P>0.05;t=0.169,0.284),and the difference was statistically significant after treatment(P<0.05;t=7.258,7.476).Conclusion The combination of traditional Chinese and western medicine for the treatment of cirrhosis with hepatic encephalopathy is effective,and the liver function of patients is improved obviously,which can be clinically promoted.

关 键 词：肝硬化 肝性脑病 肝功能 丙氨酸转氨酶 

分 类 号：R259[医药卫生—中西医结合]