基于多指标权重分析和均匀设计法优选人参提取工艺  

Extraction Technology Optimization of Ginseng Based on Multi-index Weight Analysis and Uniform Design

作　　者：王永祥 朱志军[1] 李莹丽[1] 李颖[1] 党晓月 Wang Yongxiang;Zhu Zhijun;Li Yingli;Li Ying;Dang Xiaoyue(Henan University of Chinese Medicine,Zhengzhou 450046,China)

机构地区：[1]河南中医药大学,郑州450046

出　　处：《中国药师》2020年第2期345-348,共4页China Pharmacist

基　　金：河南省科技攻关计划(编号:162102310450);2020年度河南省高等学校重点科研项目(编号:20B360007)。

摘　　要：目的:优选人参提取工艺,为生脉分散片的研究奠定基础。方法:以人参总皂苷、人参皂苷Rg1、人参皂苷Re、人参皂苷Rb1含量和浸膏得率为评价指标,采用层次分析法(AHP)、CRITIC法、AHP-CRITIC混合加权法确定权重,结合均匀试验结果优选提取工艺的最佳参数。结果:最佳提取工艺为12倍85%乙醇,回流提取2次,每次2 h。结论:AHP-CRITIC混合加权法真实客观,优化得到的最佳提取工艺重复性好,简单可行。Objective:To optimize the extraction technology of ginseng to lay foundation for the research of Shengmai dispersible tablets.Methods:The contents of total ginsenoside,ginsenoside Rg--1,ginsenoside Re and ginsenoside Rb--1,and the yield of extract were used as the evaluation indices.The weights were determined by analytic hierarchy process(AHP),criteria importance through intercriteria correlation(CRITIC)and AHP-CRITIC combined with weighting,and the parameters of the extraction technology were optimized by uniform test.Results:The optimal extraction technology was 12 times of 85%ethanol and refluxed for twice with 2 h for each time.Conclusion:AHP-CRITIC combined with weighting method is objective and reproducible,indicating that the optimal extraction technology is reasonable,stable and feasible.

关 键 词：人参 权重分析 均匀设计试验 AHP-CRITIC混合加权法 提取工艺 

分 类 号：R284.2[医药卫生—中药学]