新型冠状病毒肺炎74例临床特性分析  

Analysis of the clinical characteristics of 74 cases with Corona Virus Disease 2019

作　　者：翟蕙[1] 吴取梅 李文静[1] 刘恩惠 刘传苗[1] ZHAI Hui;WU Qu-mei;LI Wen-jing;LIU En-hui;LIU Chuan-miao(Department of Infectious Disease,The First Affiliated Hospital of Bengbu Medical College,Bengbu Anhui 233004,China)

机构地区：[1]蚌埠医学院第一附属医院感染性疾病科,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2020年第4期429-432,共4页Journal of Bengbu Medical College

摘　　要：目的:对新型冠状病毒肺炎确诊病人的临床特性进行分析并总结。方法:回顾性分析蚌埠医学院第一附属医院2020年1月22日至3月4日收治的74例新型冠状病毒肺炎的临床特性,重点对比普通型及(危)重型病人临床特性的区别。结果:74例病人中普通型35例,重型及危重型39例;家族聚集性发病的病人较多(37例,50. 0%);一般资料方面,(危)重型病人的年龄、合并其他基础性疾病率以及合并2种及2种以上基础疾病率均高于普通型病人(P <0. 05~P <0. 01);临床症状方面,(危)重型病人发病至就诊的时间较普通型长,最高体温、胸闷发生率、呼吸困难发生率较普通型高(P <0. 05~P <0. 01);实验室检查方面,(危)重型和普通型相比较,白细胞、中性粒细胞绝对值、中性粒细胞百分比、C反应蛋白以及白细胞介素-6较高,而淋巴细胞绝对值、淋巴细胞百分比和白蛋白较低(P <0. 05~P <0. 01);胸部高分辨率CT检查均出现斑片状磨玻璃影。结论:蚌埠地区病人聚集性病例较多;(危)重症病人以年龄偏大、合并基础病多、全身炎症反应大为特点。Objective:To analyze the clinical characteristics of 74 patients with corona virus disease 2019(COVID-19).Methods:The clinical characteristics of 74 pateints with COVID-19 from January 22 to March 4,2020 from the First Affiliated Hospital of Bengbu Medical College were retrospectively analyzed,and the clinical characteristics were compared between common type and severe type patients.Results:Among 74 patients,35 cases were the common type,and 39 cases were severe/critical type cases.There were high number of familial cluster(37 cases,50.0%).The age,and rates of complicated with other basic diseases and complicated with two or more basic diseases in severe/critical patients were higher than those in common patients(P<0.05 to P<0.01).In terms of clinical symptoms,the time from onset to see doctor in severe/critical patients was longer than that in common patients,and the highest body temperature,incidence rates of chest tightness and dyspnea in severe/critical patients were higher than those in common patients(P<0.05 to P<0.01).In terms of laboratory examination,the absolute value of leucocyte and neutrophil,percentage of neutrophil,C-reactive protein and interleukin-6 in severe/critical patients were higher compared with those in common patients,and the absolute value of lymphocyte,percentage of lymphocyte and albumin in severe/critical patients were lower compared with those in common patients(P<0.05 to P<0.01).The patchy ground glass opacity in chest CT of all cases were found.Conclusions:The number of familial clustering cases of COVID-19 in Bengbu city is more,and the elderly complicated with more basic diseases and systemic inflammatory response are the clinical characteristics of severe/critical patients.

关 键 词：新型冠状病毒肺炎 临床特性 

分 类 号：R563.1[医药卫生—呼吸系统]