蜚蠊目RNA干扰的应用研究进展及展望  

作　　者：马云峰 李绍斌[1,2] 杨松 黎玄钢[1,2] 

机构地区：[1]贵州大学化学与化工学院 [2]贵州大学精细化工研究与开发中心,贵阳550025

出　　处：《科技视界》2020年第12期173-175,共3页Science & Technology Vision

基　　金：贵州大学‘SRT计划’资助项目,合同号:贵大SRT字(2018)351号。

摘　　要：蜚蠊目昆虫的一些成员是世界公认的害虫,严重影响人类生活健康,采用RNA干扰(RNAi)技术可以减少蜚蠊目昆虫的数量以及疾病的传播。RNA干扰是外源性或内源性双链RNA经过Dicer酶加工处理为小干扰RNA(siRNA)与标靶基因结合,使相应标靶基因沉默的现象,从而阻止某一基因功能在细胞或整体水平上的表达,具有高效性和特异性等优势。RNAi技术作为研究基因功能的研究工具被广泛运用,并显示出开发新型有害生物管理策略的巨大潜力。近年来,此技术已被广泛成功应用于多种昆虫中,目前为止,只有较少文献关于蜚蠊目昆虫RNAi的报道。本文综述了RNAi在蜚蠊目中的应用研究进展,并展望了今后的研究方向。Some members of the order Insects are world-class pests that seriously affect human life and health.The use of RNA interference(RNAi)technology can reduce the number of orders and the spread of diseases.RNA interference is a phenomenon in which exogenous or endogenous double-stranded RNA is processed by Dicer enzymes into small interfering RNA(siRNA)that binds to the target gene and silences the corresponding target gene,thereby preventing a gene from functioning in the cell or the whole.Expression at the level has advantages such as efficiency and specificity.RNAi technology is widely used as a research tool to study the function of genes and shows great potential for developing new pest management strategies.In recent years,this technology has been widely used in a variety of insects.So far,there are only a few reports about RNAi.This article summarizes the research progress of RNAi application in the project and looks forward to the future research directions.

关 键 词：蜚蠊目 基因 RNA干扰 双链RNA 研究进展 

分 类 号：Q943[生物学—植物学]