南阳地区学龄前儿童反复呼吸道感染的影响因素分析  

Analysis of the influencing factors of recurrent respiratory tract infection in preschool children in Nanyang City

作　　者：齐芳 王书举[1] QI Fang;WANG Shuju(Nanyang Central Hospital,Nanyang 473000,China)

机构地区：[1]南阳市中心医院儿科二病区,河南南阳473000

出　　处：《河南大学学报（医学版）》2020年第1期47-49,共3页Journal of Henan University:Medical Science

基　　金：南阳市科技攻关项目(2016KJGG097)。

摘　　要：[目的]探讨南阳地区学龄前儿童反复呼吸道感染(RRTI)的影响因素。[方法]选择医院2017年1月至2019年1月期间收治的137例学龄前RRTI患儿作为病例组,同时按照年龄匹配和1∶1的比例选择同期收治的137例呼吸道感染患儿作为对照组,使用自制调查问卷调查相关资料,并采集外周血标本进行实验室检查,应用Logistic回归分析相关影响因素。[结果]单因素分析结果显示:家庭成员吸烟、早产、哮喘史、营养不良、过敏原、抗菌药物使用、户外运动时间、BALP阳性是RRTI发生的相关因素,以上χ^2值依次为4.445、5.738、6.243、5.118、23.228、17.207、4.736、20.758,均P<0.05;Logistic分析结果显示,影响学龄前儿童RRTI的因素包括早产、哮喘史、营养不良、过敏原、抗菌药物使用和BALP,上述因素OR值依次为1.726、2.761、0.713、1.894、1.928、1.337,均P<0.05;哮喘史OR值=2.761,为最大值,提示哮喘对RRTI的发生影响最大,其次是营养不良、抗菌药物使用、过敏原、EBV-IgM、早产、BALP。[结论]学龄前儿童RRTI的发生是多因素共同作用的结果,主要与哮喘、营养不良、滥用抗菌药物、过敏原、早产和缺乏维生素D有关,临床防治需要采取综合措施。[Objective]To explore the influencing factors of recurrent respiratory tract infection(RRTI) in preschool children in Nanyang city.[Methods]137 cases of preschool RRTI admitted to the hospital from January 2017 to January 2019 were selected as case group, and 137 cases of respiratory tract infection in the same period were selected as control group according to age matching and 1∶1 ratio. Salf-made paper-based questionnaire to investigate the relevant data and peripheral blood samples were collected for laboratory examination. Logistic regression was used to analyze of relevant influencing factors. [Results]The results of univariate analysis showed that smoking, premature delivery, asthma history, malnutrition, allergens, antibiotic use, outdoor exercise time and positive BALP were risk factors for RRTI, The above chi square values were 4.445、5.738、6.243、5.118、23.228、17.207、4.736、20.758 respectively,P<0.05;The results of logistic analysis showed that the factors influencing RRTI of preschool children included premature delivery, asthma history, malnutrition, allergens, antibiotic use and BALP, The OR values of the above factors were 1.726、2.761、0.713、1.894、1.928、1.337 respectively(P<0.05).[Conclusion] the occurrence of RRTI in preschool children is the result of multiple factors. It is mainly related to asthma, malnutrition, antimicrobial abuse, allergen, EBV infection, premature delivery and vitamin D deficiency. Comprehensive measures should be taken for clinical prevention and treatment.

关 键 词：反复呼吸道感染 儿童 影响因素 

分 类 号：R725.6[医药卫生—儿科]