Synergetic organocatalysis for stereoregular ring-opening polymerization of O-carboxyanhydrides to isotactic functionalized polyesters  

作　　者：Luan Shifang 

机构地区：[1]State Key Laboratory of Polymer Physics and Chemistry,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China

出　　处：《材料导报》2020年第12期12001-12002,共2页Materials Reports

摘　　要：Polyesters,such as polylactide(PLA),are a class of biodegra-dable and biocompatible polymers that have received increasing attention in biomedicine,agriculture,and commodity thermoplastics[1-2].However,the lack of pendant functionality of conventional polyesters makes it difficult to modify and modulate the physicochemical properties in subsequent applications[3-4].Since 2006[5],the ring-opening polymerization(ROP)of O-carbox-yanhydrides(OCAs),which can be readily synthesized from amino acid or hydroxyl acid precursors,has been recognized as a promising route to functionalized polyesters[3-4].However,due to the increased methine C-H acidity,significant racemization of the stereogenic center and decreased stereoregularity have been identified for most OCAs,for instance,ManOCA[6](OCA from mandelic acid)and SerOCA[7](OCA from serine),when using typical 4-(dimethylamino)pyridine(DMAP)as catalyst.To minimize epimerization,some classical metal-based catalysts of coordination polymerization have been introduced to mediate ROP of OCAs,furnishing isotactic polyesters[8].

关 键 词：POLYESTER polymerization stereo 

分 类 号：O62[理学—有机化学]