炉甘石生品及炮制品X射线衍射指纹图谱分析  

Analysis of X-ray diffraction fingerprint of Calamina and its processed products

作　　者：余倩倩 黄小清 殷钲皓 龙倩倩 韩泳平 YU Qian-qian;HUANG Xiao-qing;YIN Zheng-hao;LONG Qian-qian;HAN Yong-ping(College of Pharmacy,Southwest Minzu University,Chengdu 610041,China)

机构地区：[1]西南民族大学药学院,四川成都610041

出　　处：《中草药》2020年第7期1868-1877,共10页Chinese Traditional and Herbal Drugs

基　　金：国家“十二五”科技支撑计划(2012BAI27B07);西南民族大学中央高校基本科研业务费资助(2020NYB34)。

摘　　要：目的建立炉甘石生品及炮制品的X射线衍射(XRD)指纹图谱;比较不同炮制方法对药材主要成分的影响;测定炮制品中ZnO含量。方法采用XRD法对10批炉甘石生品及炮制品进行分析,分别建立了生品及炮制品的指纹图谱;对6种不同炮制方法进行比较;运用K值法测定了炮制品中ZnO的含量。结果分别建立了炉甘石生品和炮制品的XRD指纹图谱,其中生品XRD指纹图谱有23个共有峰,炮制品XRD指纹图谱有10个共有峰,经煅烧炮制之后生品的ZnCO3特征峰转变为ZnO的特征峰;煅烧炮制品中ZnO的含量均超过56%。结论XRD指纹图谱可用于炉甘石生品及炮制品的鉴定与分析,为炉甘石生品及炮制品的质量评价提供了新的可靠方法。Objective To establish X-ray diffraction(XRD)fingerprint of Calamina and its processed products,compare the effects of different processing methods on the main components of medicinal materials and determine the content of ZnO in the processed products.Methods XRD was used to analyze 10 batches of Calamina and its processed products,and fingerprints of Calamina and its processed products were established respectively.Six different processing methods were compared,and the content of ZnO in all processed products was determined by K value method.Results Fingerprints of Calamina and its processed products were preliminarily established.There were 23 common peaks in the fingerprints of Calamina,and there were 10 common peaks in the fingerprints of its processed products.After calcination,the ZnCO3 characteristic peak of the raw material was transformed into the characteristic peak of ZnO;The content of ZnO in the calcined product exceeded 56%.Conclusion XRD fingerprints could be used for the identification and analysis of Calamina and its processed products.The new and reliable method was provided for quality evaluation of Calamina and its processed products.

关 键 词：炉甘石 炮制 X射线衍射 指纹图谱 K值法 ZNO 质量评价 

分 类 号：R286.02[医药卫生—中药学]