磷酸钠盐和聚乙二醇用于老年患者术前肠道准备的耐受性与依从性比较  

Comparison of Tolerance and Compliance of Sodium Phosphate and Polyethylene Glycol for Preoperative Intestinal Preparation in Older Patients

作　　者：杨贞[1] 蒙有轩[1] 李金蓉[1] Yang Zhen;Meng Youxuan;Li Jinrong(Department of Urology,the People's Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,China)

机构地区：[1]广西壮族自治区人民医院泌尿外科,南宁530021

出　　处：《国际老年医学杂志》2020年第3期181-184,共4页International Journal of Geriatrics

基　　金：广西壮族自治区医疗卫生自筹经费计划课题项目(Z2012278)。

摘　　要：目的比较磷酸钠盐和聚乙二醇电解质用于老年患者术前肠道准备的耐受性与依从性。方法选择广西壮族自治区人民医院泌尿外科择期手术老年患者180例,随机分为磷酸钠盐组和聚乙二醇组,磷酸钠盐组术前1 d下午4:00磷酸钠盐口服溶液稀释后服用进行肠道准备,聚乙二醇组相同时间服用稀释后聚乙二醇电解质散剂行肠道准备,比较两组患者肠道清洁效果,服药的耐受情况,愿意再次肠道准备的依从性以及不良反应。结果磷酸钠盐组和聚乙二醇组分别有96.7%和73.3%的患者完成服药,差异有统计学意义(P<0.01);磷酸钠盐组患者肠道清洁满意率95.6%,聚乙二醇组患者为71.1%,差异有统计学意义(P<0.01);愿意再做同样的肠道准备磷酸钠盐组为94.4%,聚乙二醇组为64.4%,差异有统计学意义(P<0.01);不良反应的发生率磷酸钠盐组明显低于聚乙二醇组,差异有统计学意义(P<0.01)。结论口服磷酸钠盐在老年患者术前肠道准备肠道清洁效果好,不良反应少,患者耐受性和依从性高,值得在老年人术前肠道准备中推广应用。Objective To compare the tolerance and compliance of sodium phosphate and polyethylene glycol for preoperative intestinal preparation in older patients.Methods 180 patients with selective operation in department of urology in the Ppeople's Hospital of Guangxi Zhuang Autonomous Region were enrolled.The patients were randomly divided into sodium phosphate group and polyethylene glycol group.For preoperative intestinal preparation,at 4 p.m.the day before surgery,the sodium phosphate group received the diluted sodium phosphate oral solution,while the polyethylene glycol group received the diluted polyethylene glycol electrolyte oral solution.The intestinal cleaning effect,tolerance of medication,compliance with intestinal preparation and adverse reactions were compared between the two groups.Results 96.7%of patients in the sodium phosphate and 73.3%of patients in the polyethylene glycol group completed taking medication(P<0.01).The satisfaction rate of intestinal cleanliness was 95.6%in the sodium phosphate group and 71.1%in the polyethylene glycol group,respectively(P<0.01).94.4%of patients in the sodium phosphate group and 64.4%of patients in polyethylene glycol group would like to accept the same intestinal preparation(P<0.01).The incidence of adverse reactions in sodium phosphate group was significantly lower than those in the polyethylene glycol group(P<0.01).Conclusion Oral sodium phosphate exhibits a good intestinal clearance,few adverse reactions,and high tolerance and compliance in older patients.

关 键 词：磷酸钠盐 聚乙二醇 老年 肠道准备 

分 类 号：R699[医药卫生—泌尿科学]