黔东南侗族人群骨密度调查及相关影响因素研究  

Bone mineral density and its related influencing factors in Dong nationality,southeastern Guizhou

作　　者：邓艳 洪峰 关菡 张燕 王子云 唐学杰 尹朝晖 袁薇[4] 朱焱 DENG Yan;HONG Feng;GUAN Han;ZHANG Yan;WANG Zi-yun;TANG Xue-jie;YIN Chao-hui;YUAN Wei;ZHU Yan(The Key Laboratory of Environmental Pollution Monitoring and Disease Control of the Ministry of Education,School of Public Health,Guizhou Medical University,Guiyang,Guizhou 550025,China)

机构地区：[1]贵州医科大学公共卫生学院,环境污染与疾病监控教育部重点实验室,贵州贵阳550025 [2]贵州医科大学大学城医院,贵州贵阳550025 [3]贵州医科大学第二附属医院,贵州凯里556000 [4]贵州省疾病预防控制中心,贵州贵阳550004

出　　处：《现代预防医学》2020年第9期1641-1646,共6页Modern Preventive Medicine

基　　金：“贵州省苗族、侗族、布依族世居自然人群环境暴露与健康风险的前瞻性队列研究”(黔科合平台人才[2018]5403)。

摘　　要：目的了解当地居民骨密度流行现状及影响因素。方法多阶段抽样方法抽取黔东南侗族居民5 792名进行问卷调查、身高、体重测量,并采用超声骨密度仪测量骨密度。使用SPSS22.0对数据进行描述性分析、χ^2检验和多因素非条件logistic回归分析,探讨骨密度影响因素。结果最终纳入5 322人,黔东南侗族人群骨量减少、骨质疏松检出率分别为33.84%、2.76%,男性均高于女性。不同性别、年龄、文化程度、生活习惯、职业的居民骨质情况检出率不同(P<0.05)。经logistic回归分析,高龄(OR=1.746,95%CI=1.635~1.864)、男性(OR=2.213,95%CI=1.829~2.679)、初中(OR=1.395,95%CI=1.069~1.798)和高中文化(OR=1.292,95%CI=1.066~1.565)检出骨量减少的风险高,离退休(OR=0.681,95%CI=0.508~0.911)、体力劳动人员(OR=0.702,95%CI=0.595~0.828)、超重者(OR=0.782,95%CI=0.681~0.898)、戒烟者(OR=0.695,95%CI=0.494~0.977)检出骨量减少风险低;高龄(OR=1.903,95%CI=1.567~2.311)、男性(OR=8.744,95%CI=5.290~14.451)、体重过低(OR=3.046,95%CI=1.622~5.718)、体重肥胖(OR=3.285,95%CI=1.975~5.464)检出骨质疏松风险高,初中文化(OR=0.511,95%CI=0.287~0.910)骨质疏松检出风险低。结论贵州省黔东南侗族人群的骨量减少检出率较高,年龄、BMI、性别、文化程度可能是骨质疏松和骨量减少的影响因素。Objective To investigate the epidemic status and influencing factors of bone mineral density in local residents. Methods A total of 5792 Dong residents in Southeastern Guizhou were seleceted by multi-stage sampling, and they were investigated with the questionnaire, measuring height, weight and bone mineral density by ultrasonic bone densitometer. The general characteristics of the data and the influencing factors of BMD were analyzed by descriptive analysis, χ^2 test and multivariate unconditional logistic regression, and the statistical software is SPSS 22.0. Results In the final sample of 5322 residents, the bone mass loss rate was 33.84% and osteoporosis detection rate was 2.76%, and the detection rates of bone mass loss and osteoporosis in male were both higher than that in female. The detection rate of bone mass varied with gender, age, educational level, living habit and occupation(P<0.05). The logistic regression analysis showed that the risk of osteopenia was higher in the elderly(OR=1.746, 95%CI=1.635~1.864), male(OR=2.213, 95%CI=1.829~2.679), junior high school education level(OR=1.395, 95%CI=1.069~1.798), senior high school education level(OR=1.292, 95%CI=1.066~1.565), while lower in the retired(OR=0.681, 95%CI=0.508~0.911), physical workers(OR=0.702, 95%CI=0.595~0.828), overweight(OR=0.782, 95%CI=0.681~0.898) and ex-smoker(OR=0.695, 95%CI=0.494~0.977). The risk of osteoporosis was higher in the elderly(OR=1.903, 95%CI=1.567~2.311), male(OR=8.744, 95%CI=5.290~14.451), underweight(OR=3.046, 95%CI=1.622~5.718) and obesity(OR=3.285, 95%CI=1.975~5.464), and lower in the junior high school education level(OR=0.511, 95%CI=0.287~0.910). Conclusion The detection rate of bone mass loss is higher in Dong people in southeastern Guizhou Province. Age, BMI, gender and educational level may be the independent factors influencing osteoporosis and bone mass loss.

关 键 词：骨密度 骨量减少 骨质疏松 影响因素 

分 类 号：R580[医药卫生—内分泌]