糖尿病与腰椎间盘退变相关性研究进展  

Research progress on correlation between diabetes mellitus and lumbar disc degeneration

作　　者：王善金[1] 徐浩伟 赵卫东[1] 吴德升[1] WANG Shan-jin;XU Hao-wei;ZHAO Wei-dong;WU De-sheng(Department of Spine Surgery,Dongfang Hospital Affiliated with Tongji University,Shanghai200120,China)

机构地区：[1]同济大学附属东方医院脊柱外科,上海市200120

出　　处：《中国矫形外科杂志》2020年第9期828-831,共4页Orthopedic Journal of China

基　　金：国家自然科学基金资助项目(编号:81572181);上海市卫生计生系统优秀人才培养计划(编号:2017YQ070);浦东新区卫生系统优秀青年医学人才培养计划(编号:PWRq2016-27);浦东新区卫生系统重点学科建设资助项目(编号:PWZxk2017-08)。

摘　　要：糖尿病和腰椎间盘退变相关疾患是临床常见病多发病,两者的相互关系逐渐引起了脊柱外科医生的兴趣。本文从糖尿病和椎间盘退变的基础及临床多个方面论述两者关系的最新研究进展。椎间盘退变是多因素共同作用导致的结果,糖尿病可能是椎间盘退变相关疾患发病的危险因素之一。基础研究的进展仍未阐明潜在的机制,临床观察的结论也并不统一。正确认识糖尿病和椎间盘退变疾病之间的复杂关系,探讨糖尿病引起或加速椎间盘退变的机制,对椎间盘退变相关疾病的治疗、康复和并发症预防具有重要的临床意义。Diabetes mellitus and lumbar disc degeneration related diseases are common in clinical practice,and the rela tionship gradually aroused the interest of spine surgeons.Therefore,the research progress on this issue was reviewed from basic to clinical research in this paper.Diabetes mellitus may be one of the risk factors of disc degeneration related diseases,although the underlying mechanisms remains unclear and the conclusions of clinical observations are not uniform.Correctly understand ing the complex relationship between diabetes mellitus and disc degeneration and exploring the mechanism of diabetes induced or accelerated disc degeneration have important clinical significance for the treatment,rehabilitation,and prevention of compli cations of disc degeneration related diseases.

关 键 词：糖尿病 腰椎间盘退变 研究进展 

分 类 号：R681.57[医药卫生—骨科学]