钆布醇在腹部增强磁共振动脉血管成像中的应用价值:一项前瞻性、多中心研究  

Application value of gadobutrol in contrast-enhanced magnetic resonance angiography in abdominal artery angiography:a prospective multicenter study

作　　者：刘曦娇[1] 李峥艳[1] 张薇薇[1] 刁乙珂 付宇[2] 许乙凯[3] 王劲[4] 任静[5] 沈文[6] 宋彬[1] LIU Xijiao;LI Zhengyan;ZHANG Weiwei;DIAO Yike;FU Yu;XU Yikai;WANG Jing;REN Jing;SHEN Wen;SONG Bin(Department of Radiology,West China hospital,Sichuan University,Chengdu 610041,P.R.China;Department of Radiology,The First Hospital,Jilin University,Changchun 130021,P.R.China;Department of Radiology,Nanfang Hospital,Southern Medical University,Guangzhou,510530,P.R.China;Department of Radiology,The Third Affiliated Hospital of Zhongshan University,Guangzhou 510630,P.R.China;Department of Radiology,Sichuan Cancer Hospital,Chengdu 610041,P.R.China;Department of Radiology,Tianjin First Central hospital,Tianjin 300192,P.R.China)

机构地区：[1]四川大学华西医院放射科,成都610041 [2]吉林大学第一医院放射科,长春130021 [3]南方医科大学南方医院放射科,广州510530 [4]中山大学附属第三医院放射科,广州510630 [5]四川省肿瘤医院放射科,成都610041 [6]天津市第一中心医院放射科,天津300192

出　　处：《中国普外基础与临床杂志》2020年第5期615-618,共4页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探究钆布醇增强磁共振血管成像(MRA)在腹部动脉血管扫描的应用价值。方法前瞻性纳入2014年12月至2015年12月期间行钆布醇增强MRA检查患者112例,由两名观察者对图像质量进行分析,对大中血管行主观评分和信号值测定,对小血管进行主观评分。采用Kappa检验对两名观察者的主观评分进行一致性分析。结果最终纳入112例患者,其中96例患者因体检行腹部MRA检查,16例患者因肝脏占位行腹部MRA检查。所有患者均未发现不良反应。112例钆布醇增强MRA图像中,有2例患者因呼吸伪影严重而影响血管显影。110例MRA图像清晰,能清晰显示大中血管和小血管的起源、走行。大中血管成像的主观评分为(21.22±1.93)分,对小血管成像的主观评分为(6.24±1.33)分。对感兴趣区大中血管的信号强度测量显示信号噪声比和对比信号噪声比率分别为1093.27±331.71和897.27±333.29。两名观察者对大中血管定性分析的一致性Kappa值为0.782,对小血管定性分析的一致性Kappa值为0.772。结论钆布醇增强MRA能清晰显示大中血管,还能良好显示部分小血管,在腹部动脉血管扫描中具有良好的应用价值。Objective To explore the value of gadobutrol enhanced magnetic resonance angiography(MRA)in abdominal artery angiography.Methods The patients were prospectively included for gadobutrol enhanced MRA examination from December 2014 to December 2015.The image quality was assessed by two radiologists.The subjective score and signal intensity were measured for the large and medium arteries,and the subjective score for the small artery was recorded.The Kappa consistency analysis was used to assess the two radiologists’subjective score.Results All 112 patients were enrolled in this study,96 of whom were included for the physical examination,16 of whom were included for the liver tumors.No adverse reactions were found in these patients.The MRA images of 2 patients were affected by the severe respiratory artifact.The MRA images of the other 110 cases were clear and could well show the origins,shapes of large and medium arteries and small arteries.The subjective scores were 21.22±1.93 and 6.24±1.33 of the large and medium arteries and small arteries,respectively.The values of signal noise ratio and contrast signal noise ratio of the large and medium arteries were 1093.27±331.71 and 897.27±333.29,respectively.The Kappa values of the two radiologists’subjective score were 0.782 and 0.772 for the large and medium arteries and small arteries,respectively.Conclusions Gadobutrol enhanced MRA can clearly display large and medium arteries,and can also display some small arteries.It has a good application value in abdominal artery angiography.

关 键 词：钆布醇 磁共振血管成像 动脉血管 腹部 

分 类 号：R445.2[医药卫生—影像医学与核医学]