Photoredox/palladium-cocatalyzed enantioselective alkylation of secondary benzyl carbonates with 4-alkyl-1,4-dihydropyridines  

作　　者：Xu Shen Linlin Qian Shouyun Yu 

机构地区：[1]State Key Laboratory of Analytical Chemistry for Life Science,Jiangsu Key Laboratory of Advanced Organic Materials,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210023,China

出　　处：《Science China Chemistry》2020年第5期687-691,共5页中国科学（化学英文版）

基　　金：supported by the National Natural Science Foundation of China(21971110,21732003)。

摘　　要：A photoredox/palladium-cocatalyzed enantioselective alkylation of racemic secondary carbonates with 4-alkyl-1,4-dihydropyridines under visible light irradiation has been developed. The present study provides a method for the preparation of optically active diarylalkanes from racemic diarylmethyl carbonates by a dynamic kinetic asymmetric transformation(DYKAT).This photoredox/palladium dual catalysis strategy expands the scope of the asymmetric Pd-catalyzed benzylic substitution reaction and serves as its potential alternative and complement.

关 键 词：photoredox catalysis PALLADIUM dual catalysis photochemistry benzylic alkylation 

分 类 号：O644.1[理学—物理化学] O621.255.8[理学—化学]