孕产史与围绝经期女性冠心病的关系  

Relationship Between Motherhood History and Coronary Heart Disease in Perimenopausal Women

作　　者：张静[1] 王志宏[1] 王杰 刘桂琴[3] 田熹 秦燕 刘亚曼 ZHANG Jing;WANG Zhi-hong;WANG Jie;LIU Gui-qin;TIAN Xi;QIN Yan;LIU Ya-man(Department of Obstetrics,the Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China;Department of Physical Examination,the Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China;Department of Cardiology,the Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China)

机构地区：[1]承德医学院附属医院产科,河北承德067000 [2]承德医学院附属医院体检科,河北承德067000 [3]承德医学院附属医院心内科,河北承德067000

出　　处：《医学信息》2020年第5期111-113,共3页Journal of Medical Information

摘　　要：目的探讨孕产史与围绝经期女性冠心病的关系。方法回顾性分析2018年8月~2019年8月我院收治的226例女性冠心病患者作为病例组,另选取同期来我院体检的314名健康女性作为对照组,比较两组一般状况、孕产史、不良孕产史,采用多因素Logistic回归分析围绝经期女性发生冠心病的影响因素。结果两组身高、体重、体重指数、流产次数比较,差异无统计学意义(P>0.05);两组孕次、产次、首次分娩年龄比较,差异有统计学意义(P<0.05);两组早产、妊娠高血压疾病、产后出血、死胎、葡萄胎、异位妊娠、新生儿窒息、胎儿畸形、胎膜早破比较,差异无统计学意义(P>0.05);多因素Logistic回归分析显示,首次分娩年龄是围绝经期女性发生冠心病的保护因素,产次为围绝经期女性发生冠心病的危险因素。结论首次分娩年龄、产次是影响围绝经期女性发生冠心病的因素,临床上对具有相关临床特征的患者,应制定相应的预防措施,对重点人群进行重点关注,加强育龄妇女的健康教育,宣传和普及女性保健相关知识,尽量减少围绝经期冠心病的发生。Objective To explore the relationship between pregnancy history and coronary heart disease in perimenopausal women.Methods A retrospective analysis of 226 female patients with coronary heart disease admitted in our hospital from August 2018 to August 2019 was used as a case group,and another 314 healthy women who received physical examination in our hospital during the same period were selected as the control group.Birth history,history of adverse pregnancy and birth,multivariate Logistic regression was used to analyze the influencing factors of coronary heart disease in perimenopausal women.Results There was no significant difference in height,weight,body mass index,and number of miscarriages between the two groups(P>0.05);there was a statistically significant difference between the two groups in the age of pregnancy,parity,and first childbirth(P<0.05);There were no significant differences in preterm birth,pregnancy-induced hypertension,postpartum hemorrhage,stillbirth,hydatidiform mole,ectopic pregnancy,neonatal asphyxia,fetal malformation,and premature rupture of membranes(P>0.05).Multivariate Logistic regression analysis showed that:The first delivery age is a protective factor for the risk of coronary heart disease in perimenopausal women,and the parity is a risk factor for coronary heart disease in perimenopausal women.Conclusion The age and parity of the first childbirth are factors that affect the occurrence of coronary heart disease in perimenopausal women.Clinically,patients with relevant clinical characteristics should formulate corresponding preventive measures,focus on key populations,and strengthen health education for women of childbearing age.Promote and popularize women's health-related knowledge and minimize the incidence of perimenopausal coronary heart disease.

关 键 词：孕产史 围绝经期 冠心病 危险因素 

分 类 号：R541.4[医药卫生—心血管疾病]