微波消解-ICP-AES法测定硫熏对党参重金属及微量元素含量的影响  

Study on determination of heavy metals and trace elements in sulfur- fumigated Radix Codonopsis by microwave digestion-ICP-AES method

作　　者：杨军宣[1] 张毅 廖江敏 王刚[1] 喻录容[1] 吕志勇[1] YANG Jun-xuan;ZHANG Yi;LIAO Jiang-min;WANG Gang;YU Lu-rong;LYU Zhi-yong(TCM School of Chongqing Medical University,Chongqing 400016,China;Chongqing Institute for Food and Drug Control,Chongqing 401121,China)

机构地区：[1]重庆医科大学中医药学院,重庆400016 [2]重庆市食品药品检验检测研究院,重庆401121

出　　处：《天然产物研究与开发》2020年第4期689-693,606,共6页Natural Product Research and Development

基　　金：国家药典委员会项目(ZG2016-2-06);重庆市卫生和计划生育委员会中医药科技项目(ZY201702132)。

摘　　要：采用硝酸消解党参,建立电感耦合等离子体原子发射光谱法(ICP-AES)测定党参及硫磺熏蒸党参药材的重金属(Cu、Cd、Pb、Hg、As)及微量元素(Al、Cr、Fe、Mg、Zn、P、K、Ca)含量变化,研究传统硫磺熏蒸方法对党参重金属及微量元素含量的影响。结果表明,党参经硫磺熏蒸后镉(Cd)含量增加63.51%,铅(Pb)含量增加35.47%,砷(As)含量增加108.63%。Fe含量减少36.64%,K含量减少20.48%。党参硫磺熏蒸后重金属及微量元素含量有显著变化,应加强检测,以便全面评价和控制党参药材质量,确保临床用药安全。To establish a method for the determination of heavy metals and trace elements in Radix Codonopsis by microwave digestion-ICP-AES,study the effects of sulfur fumigation on the heavy metals and trace elements in Radix Codonopsis.Contents of heavy metals(Cu,Cd,Pb,Hg,As) and trace elements(Al,Cr,Fe,Mg,Zn,P,K,Ca) in Radix Codonopsis were determined by ICP-AES after digestion with nitric acid.The results showed that Cd,Pb and As increased by 63.51%,35.47% and 108.63% in sulfur-fumigated Radix Codonopsis.The Fe and K decreased by 36.64% and 20.48% in sulfur-fumigated Radix Codonopsis.To sum up,the content of heavy metals and trace elements in Radix Codonopsis after sulfur fumigation changed significantly.we should strengthen the detection so as to control the quality and ensure the safety of Radix Codonopsis.

关 键 词：微波消解 党参 硫磺熏蒸 重金属 微量元素 

分 类 号：R283.1[医药卫生—中药学]