CTA结合CTP对预测急性脑梗死患者静脉溶栓预后的价值  

The value of CTA combined with CTP in predicting the prognosis of intravenous thrombolysis in patients with acute cerebral infarction

作　　者：沈永玲[1] 朱海暴[1] 李勇[1] 朱云波[2] SHEN Yong-ling;ZHU Hai-bao;LI Yong;ZHU Yun-bo(Department of Neurology,1.Chengde Central Hospital;Affiliated Hospital of Chengde Medical College,Chengde 067000,Hebei,China)

机构地区：[1]承德市中心医院神经内科 [2]承德医学院附属医院神经内科,河北承德067000

出　　处：《川北医学院学报》2020年第2期280-282,共3页Journal of North Sichuan Medical College

基　　金：河北省承德市科学技术研究与发展计划项目(201422005)。

摘　　要：目的:探究CT血管成像(CTA)结合CT灌注成像(CTP)预测急性脑梗死患者静脉溶栓预后的价值。方法:78例急性脑梗死患者均行CTA和CTP检查,根据检查结果所有患者分为A组(CTA和CTP均为阳性,n=36)、B组(CTA阳性,CTP阴性,n=12)、C组(CTA阴性,CTP阳性,n=21)、D组(CTA和CTP均为阴性,n=9)。治疗24 h内,采用卒中量表(NIHSS)评分评估近期预后效果;治疗3个月后,采用改良Rankin量表(mRS评分)评估远期预后。结果:治疗后,A组NIHSS评分低于其余3组,B组和C组NIHSS评分低于D组,差异有统计学意义(P<0.05);而B组和C组NIHSS评分比较,差异无统计学意义(P>0.05)。治疗3个月后,A组mRS评分≤2分的患者显著多于其余3组,差异有统计学意义(P<0.05);B组、C组、D组间比较,差异无统计学意义(P>0.05)。结论:CTA结合CTP对预测急性脑梗死患者静脉溶栓预后有一定指导意义。Objective:To investigate the value of CT angiography(CTA)combined with CT perfusion imaging(CTP)in predicting the prognosis of intravenous thrombolysis in patients with acute cerebral infarction.Methods:A total of 78 patients with acute cerebral infarction underwent CTA and CTP examinations.They were divided into group A(CTA positive,CTP positive,n=36),group B(CTA positive,CTP negative,n=12),group C(CTA negative,CTP positive,n=21)and group D(CTAnegative,CTP negative,n=9)according to the results of examination.The short-term prognosis effects were assessed using the NIHSS score within 24 h of treatment.The long-term prognosis was assessed using the modified Rankin scale(mRS score)after 3 months of treatment.Results:After treatment,the NIHSS score in group A was significantly lower than that in the other three groups,and the NIHSS score in group B and group C was significantly lower than that in group D,the difference was statistically significant(P<0.05),and there was no statistically significant difference in the NIHSS score between group B and group C(P>0.05).After 3 months of treatment,the number of patients with mRS score≤2 points in group A was significantly more than that in the other three groups,the difference was statistically significant(P<0.05),and there was no significant difference among group B,group C and group D(P>0.05).Conclusion:CTA combined with CTP has a certain guiding significance for predicting the prognosis of intravenous thrombolysis in patients with acute cerebral infarction.

关 键 词：CT血管成像 CT灌注成像 急性脑梗死 静脉溶栓 预后 

分 类 号：R816.1[医药卫生—放射医学]