α-酮戊二酸的代谢机理、营养生理功能及其在养殖生产中的应用  

The Metabolic Mechanism and Nutritional Physiological Function of α-ketoglutarate and Its Application in Livestock Production

作　　者：李硕 邹田德 王自蕊[1] 游金明[1] LI Shuo;ZOU Tiande;WANG Zirui;YOU Jinming(Jiangxi Province Key Laboratory of Animal Nutrition/Jiangxi Province Key Innovation Center for Industry-Education Integration of High Quality and Safety Livestock Production,Jiangxi Agricultural University,Nanchang 330045,China)

机构地区：[1]江西农业大学,江西省动物营养重点实验室/江西省优质安全畜禽生产产教融合重点创新中心,南昌330045

出　　处：《畜牧兽医学报》2020年第5期923-932,共10页ACTA VETERINARIA ET ZOOTECHNICA SINICA

基　　金：中国博士后科学基金面上项目(2019M662270)。

摘　　要：α-酮戊二酸(alpha-ketoglutarate,AKG)是谷氨酸和谷氨酰胺的前体物质,三羧酸循环(tricarboxylic acid cycle,TCA cycle)的重要中间物质,可作为谷氨酰胺最佳替代物。近年来,AKG因其良好的稳定性和独特的营养生理功能,受到研究者的广泛关注,并作为新型的功能性饲料添加剂应用于动物生产,对发展生态健康养殖业具有重要意义。本文就AKG的代谢机理、营养生理功能及其在养殖生产中的应用现状进行综述,旨在为AKG在养殖生产中的合理应用提供指导依据。α-ketoglutarate(AKG),an important intermediate in the cycle of tricarboxylic acid(TCA),is a precursor of glutamic acid and glutamine,also the best substitate of glutamine.As a new functional feed additive for animal production,AKG is receiving more and more attention recently due to its good stability and unique nutritional physiological functions,which will be of great significance for the development of ecological health breeding industry.This paper reviews the metabolic mechanism,nutritional physiological function and application of AKG in animal production,which would provide a direction for the further study and rational application of AKG.

关 键 词：Α-酮戊二酸 代谢机理 营养学功能 动物生产应用 

分 类 号：S816.7[农业科学—饲料科学]