含两性离子前体聚氨酯的合成及防污性能研究  

Development of polyurethane with zwitterionic precursors and their antifouling properties

作　　者：曹耀匀 马骏 吴碧梅[1] 夏枚生 陈圣福[1] CAO Yao-yun;MA Jun;WU Bi-mei;XIA Mei-sheng;CHEN Sheng-fu(College of Chemical and Biological Engineering,Zhejiang University,Hangzhou 310027,China;Ocean College,Zhejiang University,Zhoushan 316021,China)

机构地区：[1]浙江大学化学工程与生物工程学院,浙江杭州310027 [2]浙江大学海洋学院,浙江舟山316021

出　　处：《高校化学工程学报》2020年第2期512-518,共7页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金(21674092,21474085);国家重点基础研究发展计划(973计划)(2015CB655303)。

摘　　要：防污材料能够有效应对生物医学排异反应和海洋生物污损。羧酸甜菜碱类似物水解而得的两性离子具有优异的亲水性,易形成长效防污表面而被广泛研究。乙基取代叔胺型羧酸甜菜碱酯(TECBT)可作为两性离子前体引入改良的聚氨酯中制得具有优异物理性能的防污材料。其水解前后的化学结构通过衰减全反射红外光谱(ATR-IR)表征,亲疏水能力通过接触角表征,防污性能通过蛋白质、细菌、细胞吸附实验表征。结果表明,聚氨酯材料水解后生成了亲水性的两性离子,不仅能强效持久地抗蛋白质吸附,也能抵抗细菌与细胞吸附,具有优异的防污性能。Antifouling is one of the most important methods to cope medical rejection and marine biofouling. Zwitterions which are hydrolyzed by carboxylate betaine analogue have good hydration ability to form antifouling surface. In this study, tertiary ethyl substituted carboxybetaine t-butyl(TECBT) was introduced into modified polyuretha(PU) as zwitterionic precursor. Their structures and antifouling properties were studied by ATR-IR, static contact angle measurement, protein, bacterial and cell attachment tests before and after hydrolysis. The results indicate that the new PU exhibits long-term resistance to protein, bacterial and cell attachment after hydrolysis.

关 键 词：聚氨酯 羧酸甜菜碱 水解 两性离子 防污性能 

分 类 号：TB34[一般工业技术—材料科学与工程]