抑郁症与老年性骨质疏松之间的相关性  

Relationship between depression and senile osteoporosis

作　　者：王凯 宋敏[1,2] 宋志靖 文皓楠[1] 张亚彬 WANG Kai;SONG Min;SONG Zhijing;WEN Haonan;ZHANG Yabin(Gansu University of Traditional Chinese Medicine, Lanzhou 730000;Affiliated Hospital of Gansu University of Traditional Chinese Medicine, Lanzhou 730020, China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃中医药大学附属医院,甘肃兰州730020

出　　处：《中国骨质疏松杂志》2020年第5期751-754,776,共5页Chinese Journal of Osteoporosis

基　　金：甘肃省自然科学基金计划(17JR5RA056);甘肃省中医药防治慢性疾病重点实验室开放基金项目(GSMBKY2015-07);甘肃省自然科学基金计划(1506RJZA048);甘肃省中医药管理局科研课题(GZK-2016-17);甘肃省中药现代制药工程研究院项目(YWW-2015049);研究生创新基金(CX2019-03)。

摘　　要：抑郁症与骨质疏松症是严重影响老年群体身心健康的常见疾病,随着人口老龄化趋势的加剧,二者的发病率逐年增长。老年人各组织器官开始衰老、功能逐渐退化,机体内环境发生改变,各种不良因素的交互叠加,导致骨代谢紊乱,骨吸收大于骨形成,造成骨量丢失。抑郁症属于精神心理系统疾患,近年来随着研究的不断深入,发现与骨质疏松症的发生密切相关。本文通过总结分析近几年国内外在这方面取得的最新研究进展,就抑郁症与老年性骨质疏松症之间的相关性展开综述,从而有针对性地对这两种疾病进行早期干预,对降低不良事件的发生,改善老年患者临床症状,提高晚年生活质量具有积极意义。Depression and osteoporosis are both the most common diseases that seriously affect the physical and mental health of the elderly.As the population ages,the incidence of both is increasing year by year.The decline of organs,the deterioration of function and the changes in the internal environment together cause a disorder of bone metabolism,which ultimately leads to the loss of bone mass.Depression is a mental illness.With the deepening of research on the disease,it has been found that depression has a very close relationship with osteoporosis.This paper summarizes and analyzes the recent research progress in depression and osteoporosis in China and abroad in recent years,and reviews the correlation between depression and senile osteoporosis.Therefore,targeted early intervention of the two diseases could have a positive significance for reducing the occurrence of adverse events,improving the clinical symptoms of elderly patients,and improving the quality of life in old age.

关 键 词：抑郁症 老年性骨质疏松症 发病机制 相关性 

分 类 号：R592[医药卫生—老年医学]