妇产科手术切口子宫内膜异位症的初步治疗效果  

PRELIMINARY TREATMENT OUTCOME OF SURGICAL INCISION ENDOMETRIOSIS IN OBSTETRICS AND GYNECOLOGY

作　　者：张健 赵敏[2] 王晓孟 王丹[2] 王笑峰[3] 徐琳[2] ZHANG Jian;ZHAO Min;WANG Xiaomeng;WANG Dan;WANG Xiaofeng;XU Lin(Department of Obstetrics, Guangrao County People’s Hospital, Guangrao 257300, China)

机构地区：[1]广饶县人民医院产科,山东广饶257300 [2]青岛大学附属医院产科 [3]青岛大学基础医学院病原生物学系

出　　处：《青岛大学学报（医学版）》2020年第2期199-202,共4页Journal of Qingdao University(Medical Sciences)

基　　金：国家自然科学基金面上项目(81571408);国家卫生计生委科技发展计划项目(201607)。

摘　　要：目的探讨妇产科手术切口子宫内膜异位症的治疗效果。方法选取2013年2月—2015年8月我院收治的妇产科手术切口子宫内膜异位症病人46例,随机分为观察组和对照组。观察组采用一次性病灶清除术及术前/术后药物治疗,对照组采用药物治疗,比较两组病人的临床疗效、康复周期以及住院费用。结果观察组显效率为82.6%,术后1年随访无病人复发或恶变;对照组显效率为34.8%,术后1年随访4例病人复发。观察组显效率、无效率与对照组比较,差异有统计学意义(χ2=4.792、10.850,P<0.05、0.001)。观察组康复周期为(7.5±1.9)d、治疗费用为(6954.3±95.2)元,均显著低于对照组的(14.4±1.6)d和(7187.1±135.7)元,差异有统计学意义(t=6.735、13.320,P<0.001)。结论对于妇产科手术切口子宫内膜异位症病人,药物与手术联合治疗为最佳治疗手段。Objective To investigate the treatment outcome of surgical incision endometriosis in gynecology and obstetrics.Methods A total of 46 patients with surgical incision endometriosis who were treated in our hospital from February 2013 to August 2015 were enrolled and randomly divided into observation group and control group.The patients in the observation group were given one-time debridement and preoperative/postoperative medication,and those in the control group were given medication.The two groups were compared in terms of clinical outcome,period of rehabilitation,and hospital costs.Results The observation group had a marked response rate of 82.6%,and there was no recurrence or malignant transformation during the one-year follow-up after surgery;the control group had a marked response rate of 34.8%,and 4 patients experienced recurrence during the one-year follow-up after surgery.There were significant differences in marked response rate and non-response rate between the observation group and the control group(χ2=4.792,10.850;P<0.05,0.001).Compared with the control group,the observation group had a significantly shorter period of rehabilitation(7.5±1.9 d vs 14.4±1.6 d,t=6.735,P<0.001)and significantly lower treatment costs(6954.3±95.2 yuan vs 7187.1±135.7 yuan,t=13.320,P<0.001).Conclusion Surgery combined with medication is an effective treatment method for patients with surgical incision endometriosis in gynecology and obstetrics.

关 键 词：子宫内膜异位症 外科伤口 产科外科手术 药物疗法 治疗结果 

分 类 号：R711.71[医药卫生—妇产科学] R649.9[医药卫生—临床医学]