不同血液净化模式对治疗脓毒症多脏器功能衰竭的疗效分析  

Efficacy Analysis of Different Blood Purification Modes in the Treatment of Multiple Organ Failure in Sepsis

作　　者：何亚丽[1] 张相成[1] 刘宏[1] 王新刚 邵炜慧 HE Ya-li;ZHANG Xiang-cheng;LIU Hong(Pingdingshan First People’s Hospital,Pingdingshan,Henan,467000,China)

机构地区：[1]平顶山市第一人民医院,河南平顶山467000

出　　处：《黑龙江医学》2020年第5期584-586,共3页Heilongjiang Medical Journal

摘　　要：目的研究分析不同血液净化模式治疗脓毒症多脏器功能衰竭的临床疗效。方法将于2017年1月-2018年11月间在平顶山市第一人民医院就诊的脓毒症多脏器功能衰竭患者60例作为研究对象,随机分成对照组和观察组,每组30例,对照组采取连续性静脉-静脉血液滤过治疗,观察组采取脉冲式高容量血液滤过治疗,比较两组患者的动脉氧分压与吸入氧浓度比(PaO2/FiO2)、平均动脉压(MAP)、心率(HR)、血尿素氮(BUN)。结果观察组患者的PaO2/FiO2显著高于对照组,而MAP、HR、BUN均要低于对照组(P<0.05)。结论采用脉冲式高容量血液滤过治疗模式治疗脓毒症合并多脏器功能衰竭患者,可有效清除炎症因子,改善患者的肝肾功能和预后。Objective To study and analyze the clinical efficacy of different blood purification modes in the treatment of sepsis multiple organ failure.Methods 60 patients with multiple organ function failure in the hospital from January,2017 to November,2018 were randomly divided into control group and observation group,with 30 cases in each group.The control group were treated with continuous intravenous-channels hemofiltration,and the observation group were treated with pulse type high volume hemofiltration.PaO2/FiO2,MAP,HR and BUN of two groups were recorded and compared.Results PaO2/FiO2 in the observation group was significantly higher than that in the control group,while MAP,HR and BUN were all lower than those in the control group,P<0.05.Conclusion Pulse high-volume hemofiltration therapy can effectively remove inflammatory factors,improve liver and kidney function,and improve prognosis of patients with sepsis complicated with multiple organ failure.

关 键 词：脓毒症 多脏器功能衰竭 血液净化 疗效 

分 类 号：R631.1[医药卫生—外科学] R459.7[医药卫生—临床医学]