电针治疗类风湿关节炎的研究进展  

Advance in the research of electroacupuncture in the treatment of rheumatoid arthritis

作　　者：徐武岩 查丁胜[1] 林振 黄嘉文 吴昊[1] 林宏生[1] 查振刚[1] XU Wuyan;ZHA Dingsheng;LIN Zhen;HUANG Jiawen;WU Hao;LIN Hongsheng;ZHA Zhengang(Department of Orthopedics,First Affiliated Hospital of Jinan University,Guangzhou,Guangdong 510630,China)

机构地区：[1]暨南大学附属第一医院骨科,广州510630

出　　处：《中国骨科临床与基础研究杂志》2019年第6期364-370,共7页Chinese Orthopaedic Journal of Clinical and Basic Research

基　　金：国家自然科学基金青年项目(81401766);广东省医学科研基金(B2012196);广东省科技计划项目(2017ZC0007);暨南大学科研培育与创新基金青年基金(21612303);暨南大学附属第一医院培育基金(2012-1)。

摘　　要：类风湿关节炎(RA)是造成我国人群劳动力丧失与致残的主要病因之一。该病病情复杂,病程迁延反复,目前的治疗还停留在改善患者疼痛症状、延缓关节畸形破坏的阶段,无法根治。临床及动物实验研究证实,电针治疗不仅具有良好的镇痛作用,更为重要的是可以调控炎症细胞因子及其相关信号通路,改善RA发生发展的内环境,减轻炎症反应,进而达到有效治疗的目的。本文对近年来电针治疗RA的基础和临床研究进行综述,以期更好地阐释其治疗机制,为临床应用提供借鉴和参考。Rheumatoid arthritis(RA)is one of the major causes to bring about disability and cripple in Chinese population.Because of the complicated condition,and prolonged and repeated course,RA’s treatment is still in the process of releasing pain symptoms,and delaying joint deformity and destruction,as a result,RA can not be cured radically at present.In clinical and animal experimental studies,treatment of electroacupuncture has been proved to have good analgesic effect,what’s more,it can regulate inflammatory cytokines and related signaling pathways,improve the internal environment of the occurrence and development of RA,alleviate inflammation reaction and then achieve the goal of effective treatment.In order to better elucidate the therapeutic mechanism of electroacupuncture,to provide the references and experiences for clinical application,the related documents in recent years are reviewed including fundamental and clinical studies in this paper.

关 键 词：电针 针刺疗法 关节炎 类风湿 关节炎 实验性 炎症 细胞因子类 信号传导 针刺镇痛 痛阈 内啡肽类 日常生活活动 治疗结果 

分 类 号：R245[医药卫生—针灸推拿学] R593.22[医药卫生—中医临床基础]