北沙参化学成分与药理活性研究进展  

Advances in Studies on Chemical Constituents of Glehniae Radix and Their Pharmacological Activities

作　　者：王晓琴 苏柯萌 WANG Xiao-qin;SU Ke-meng(School of Pharmacy,Inner Mongolia Medical University,Hohhot 010110,China)

机构地区：[1]内蒙古医科大学药学院,内蒙古呼和浩特010110

出　　处：《中国现代中药》2020年第3期466-474,共9页Modern Chinese Medicine

基　　金：内蒙古医科大学校级科研创新团队(YKD2017KJCXTD013);内蒙古自治区新世纪321工程。

摘　　要：北沙参为临床常用中药,也可食用。其化学成分主要为香豆素、木脂素、聚炔等类成分。现代药理研究表明,北沙参具有免疫调节、抗肿瘤、抗炎、抗氧化、保肝等方面的活性。本研究在对国内外有关北沙参的文献资料系统整理以及市场产地调研基础上,对其化学成分和药理活性进行总结,以期为北沙参的质量评价、规范化种植以及中蒙医临床使用提供可靠依据。Glehniae Radix,an edible traditional Chinese medicine.So far,chemical constituents of Glehniae Radix were reported including coumarins,lignans,and polyacetylenes.Studies on its biological activity covered immunomodulation,anti-tumor,anti-inflammatory,anti-oxidation,liver protection and so on.This review focuses on recent advances in research on chemical constituents and biological activity of Glehniae Radix.This paper can provide some guidelines for quality evaluation,standardized cultivation,and clinical medicine of Glehniae Radix in the future.

关 键 词：北沙参 珊瑚菜 香豆素 木脂素 聚炔 

分 类 号：R282.71[医药卫生—中药学] R284[医药卫生—中医学]