微RNA在下颌髁突软骨生长发育中作用的研究进展  

Advances in research of microRNA in the growth and development of mandibular condyle cartilage

作　　者：张赞赞 张佳男 夏珏瑶 卢海平[1] Zhang Zanzan;Zhang Jianan;Xia Jueyao;Lu Haiping(Faculty of Orthodontics,School of Stomatology,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Dentistry,Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou 310016,China)

机构地区：[1]浙江中医药大学口腔医学院正畸教研室,杭州310053 [2]浙江大学医学院附属邵逸夫医院牙科,杭州310016

出　　处：《中华口腔医学杂志》2020年第4期276-279,共4页Chinese Journal of Stomatology

基　　金：浙江省自然科学基金(LY19H140001)。

摘　　要：微RNA(micro RNA,miRNA)是一类小的非编码单链RNA,通过与信使RNA结合发挥其生物学作用。研究显示miRNA可能在调节下颌髁突软骨的生长发育中起重要作用。本文就miRNA的产生及其作用机制,对下颌髁突软骨生长发育相关的miRNA研究进展进行综述,以期助于进一步研究下颌髁突软骨生长发育。MicroRNA(miRNA)are a class of small non-coding single-stranded RNA that exert their biological effects by binding to target messenger RNA(mRNA).There is new evidence that miRNA may play an important role in regulating the growth and development of mandibular condylar cartilage.In this paper,the production and mechanism of miRNA are reviewed,and the progress of studies on the growth and development of mandibular condylar cartilage,which is helpful to further study the growth and development of mandibular condylar cartilage.

关 键 词：微RNAS 下颌髁突软骨 生长发育 

分 类 号：R7[医药卫生—临床医学]