β受体阻滞剂治疗甲亢性心脏病心力衰竭的效果  

Effect of β-blockers in treating hyperthyroid heart disease and heart failure

作　　者：李淡文 LI Dan-wen(Department of Endocrinology,Hanshou County People's Hospital,Changde City,Changde 415900,China)

机构地区：[1]常德市汉寿县人民医院内分泌科,湖南常德415900

出　　处：《中国处方药》2020年第5期68-69,共2页Journal of China Prescription Drug

摘　　要：目的探讨甲亢性心脏病心衰患者经β受体阻滞剂治疗的临床效果。方法2018年3月~2019年11月期间,从某院选取80例甲亢性心脏病心衰疾病患者以随机数表法为原则分为对照组(n=40,行常规药物治疗)和观察组(n=40,行常规药物治疗+β受体阻滞剂治疗)。比较两组患者治疗心功能改善情况和生活质量。结果实施治疗前,对照组与观察组的左心室射血分数、左心收缩末期内径、左心舒张末期内径差异无统计学意义(P>0.05),实施治疗后,对照组与观察组的左心室射血分数均升高,左心收缩末期内径、左心舒张末期内径均降低,组间比较观察组左心室射血分数较高,左心收缩末期内径、左心舒张末期内径较低,差异有统计学意义(P<0.05);情绪功能、角色功能、认知功能、躯体功能、社会功能以及整体功能等生存质量指标与对照组比较,观察组各指标评分均显著较高(P<0.05)。结论甲亢性心脏病心衰患者经β受体阻滞剂治疗的临床效果显著,改善了患者的心功能,且提高了患者的生活质量。Objective To investigate and analyze the clinical effect of β-receptor blockers in patients with hyperthyroid heart disease and heart failure.Methods From March 2018 to November 2019,80 patients with hyperthyroid heart disease and heart failure were selected from our hospital and divided into a control group(n=40,routine drug treatment)and observation group(n=40,conventional drug treatment+β-blocker treatment)based on the random number table method.The improvement of cardiac function and quality of life between the two groups of patients were compared.Results Before treatment,there was no significant difference in left ventricular ejection fraction,left ventricular end-systolic diameter,and left ventricular end-diastolic diameter between the control group and the observation group(P>0.05).After the treatment,in the control group and the observation group,the left ventricular ejection fraction increased,the left ventricular end-systolic diameter,and the left ventricular end-diastolic diameter decreased.In the comparison,the left ventricular ejection fraction was higher,and the left ventricular end-systolic diameter and left-end diastolic diameter were better in the observation group.Compared with the control group,the quality of life indicators such as emotional function,role function,cognitive function,physical function,social function,and overall function in the observation group were significantly lower than those in the control group(P<0.05).Conclusion The clinical effect of β-receptor blockers in patients with hyperthyroid heart disease and heart failure is significant,which improves the patient's heart function and improves the patient's quality of life,which is worthy of popularization and application.

关 键 词：Β受体阻滞剂 甲亢性心脏病 心衰 生活质量 

分 类 号：R541.6[医药卫生—心血管疾病] R541.9[医药卫生—内科学]