皮肤光老化的研究进展  

The Research Progress of Skin Photoaging

作　　者：李鹏琴 张桂云[1] 李雪(综述)[1] 姚春丽(审校)[1] LI Peng-qin;ZHANG Gui-yun;LI Xue;YAO Chun-li(Department of Dermatology,the Second Hospital of Jilin University,Changchun 130041,Jilin,China)

机构地区：[1]吉林大学第二医院皮肤科,吉林长春130041

出　　处：《中国美容医学》2020年第5期174-177,共4页Chinese Journal of Aesthetic Medicine

基　　金：吉林省科技厅国际合作项目(编号:20170414055GH);中青年科技创新领军人才及团队项目(编号:20180519006JH)。

摘　　要：人的皮肤长期受到紫外线的照射容易引起光老化,而光老化与脂溢性角化、色素斑、日光性角化病及皮肤恶性肿瘤等多种疾病的发生有关,因此,预防和改善皮肤光老化已经逐渐成为皮肤科医生研究的热点。近年来,国内外学者对光老化的研究有了新的进展,通过查阅文献,笔者主要从光老化的发生机制、光老化的防治以及α1抗胰蛋白酶在光老化中的研究进展三个方面进行综述。Photoaging could happen due to long-term exposure to ultraviolet radiation,and photoaging is also associated with seborrheic keratosis,pigmented spots,actinic keratosis,and malignant skin disease.Therefore,it has gradually become research hotspot for dermatologists on prevention and improvement of skin photoaging.In recent years,scholars have made new progress in the study of photoaging at home and abroad.The author reviews the three aspects of the mechanism of photoaging,protection and treatment of photoaging and the research progress ofα-1 antitrypsin in photoaging by consulting the literature.

关 键 词：光老化 紫外线 皮肤 机制 Α1抗胰蛋白酶 

分 类 号：R339.38[医药卫生—人体生理学]