结直肠癌患者化疗依从性及影响因素分析  

Analysis on Chemotherapy Compliance and Influencing Factors of Patients with Colorectal Cancer

作　　者：周芳燕[1] 张娅娅[1] 彭丹红[1] 杨秀英[1] ZHOU Fang-yan;ZHANG Ya-ya;PENG Dan-hong;YANG Xiu-ying(Taizhou Hospital of Zhejiang Province)

机构地区：[1]浙江省台州医院

出　　处：《医院管理论坛》2020年第2期29-30,28,共3页Hospital Management Forum

基　　金：浙江省医药卫生科技计划项目,编号:2019RC236。

摘　　要：目的探讨结直肠癌患者术后化疗依从性及其相关影响因素。方法对940例结直肠癌术后化疗的患者随访调查,采用单因素法和多因素logistic回归法分别筛选影响患者化疗依从性的因素。结果结直肠癌患者术后化疗依从性差的发生率为35.96%(338/940);多因素logistic结果显示,影响结直肠癌患者化疗依从性的因素包括家庭经济状况差(OR=3.347)、术后发生并发症(OR=4.821)、化疗不良反应(OR=5.392)、肿瘤及化疗认知差(OR=2.889)、不良心理反应(OR=3.766)等。结论结直肠癌患者术后的化疗依从性较差,应针对上述影响因素,制订相应的改进措施,提高化疗依从性,改善患者的预后。Objective To investigate the postoperative chemotherapy compliance and related influencing factors of patients with colorectal cancer. Methods A total of 940 patients with postoperative chemotherapy for colorectal cancer were followed up. Single factor and multivariate logistic regression methods were used to screen the factors affecting patients’ chemotherapy compliance. Results The incidence of poor postoperative chemotherapy compliance in colorectal cancer patients was 35.96%(338/940). Multivariate logistic results showed that factors affecting chemotherapy compliance in colorectal cancer patients included poor family economic status(OR=3.347), post operation complications(OR=4.821), adverse reactions to chemotherapy(OR=5.392), poor cognition of tumor and chemotherapy(OR=2.889), adverse psychological reactions(OR=3.766), etc. Conclusions Patients with colorectal cancer have poor postoperative chemotherapy compliance. Improving measures should be taken based on the influencing factors above, so that chemotherapy compliance and patients’ prognosis can be improved.

关 键 词：结直肠癌 化疗依从性 影响因素 

分 类 号：R197.3[医药卫生—卫生事业管理]