米索前列醇与COOK子宫颈扩张球囊在妊娠晚期促宫颈成熟中的应用效果比较  

Application effect comparison of Misoprostol and COOK cervical dilatation balloon in promoting cervical ripening in late pregnancy

作　　者：姜艳艳[1] 缪丽琳 JIANG Yan-yan;MIAO Li-lin(Department of Obstetrics,Houjie Hospital of Dongguan City in Guangdong Province,Dongguan523000,China)

机构地区：[1]广东省东莞市厚街医院产科,广东东莞523000

出　　处：《中国当代医药》2020年第13期80-82,共3页China Modern Medicine

摘　　要：目的比较米索前列醇和COOK子宫颈扩张球囊在妊娠晚期促宫颈成熟中的应用效果。方法选取2016年1月~2019年7月在我院有引产指征且宫颈评分不成熟的晚期妊娠孕妇90例作为研究对象,按抽签随机法分为米索前列醇组(A组)40例,COOK球囊组(B组)50例。比较两组治疗前后宫颈评分、分娩结局、并发症发生率及新生儿情况。结果治疗后两组的宫颈评分高于治疗前,差异有统计学意义(P<0.05)。B组促宫颈成熟有效率高于A组(P<0.05)。A组宫缩过频、胎儿窘迫发生率高于B组,差异均有统计学意义(P<0.05),两组剖宫产率、产后出血率、新生儿窒息率比较,差异无统计学意义(P>0.05)。结论COOK子宫颈扩张球囊、米索前列醇均可明显改善宫颈成熟度,但COOK子宫颈扩张球囊效果更佳,使用安全性更高,值得临床推广应用。Objective To compare the effect of Misoprostol and cook cervical dilatation balloon in promoting cervical ripening in late pregnancy.Methods Ninety late pregnant women with indications of induced labor and immature cervix from January 2016 to July 2019 in our hospital were selected as research objects.They were randomly divided into 40 cases of Misoprostol group(group A),50 cases of COOK balloon group(group B)by drawing.The cervical score before and after treatment,delivery outcome,complications and neonatal condition of pregnant women were compared between two groups.Results The cervical score of the two groups after treatment were higher than those before treatment,the differences were statistically significant(P<0.05).The effective rate of promoting cervical maturation in group B was higher than that in group A(P<0.05).The incidence of uterine contraction overfrequency and fetal distress in group A were higher than that in group B(P<0.05).There were no significant differences in cesarean section rate,postpartum hemorrhage rate and neonatal asphyxia between the two groups(P>0.05).Conclusion COOK cervical dilatation balloon and Misoprostol can significantly improve cervical ripening,but COOK cervical dilatation balloon is more safe and worthy of clinical application.

关 键 词：米索前列醇 子宫颈扩张球囊 促宫颈成熟 引产 晚期妊娠 

分 类 号：R719.3[医药卫生—妇产科学]