黄芪多糖、灵芝多糖和转移因子对犬瘟热免疫效果的影响  

Effects of astragalus polysaccharides,ganoderma polysaccharides and transfer factor on immune-efficiency to canine distemper

作　　者：孙康迪 柳青云 方咏青 程子凯 李富桂 SUN Kang-di;LIU Qing-yun;FANG Yong-qing;CHENG Zi-kai;LI Fu-gui(College of Animal Science and Veterinary Medicine,Tianjin Agricultural University,Tianjin 300384,China)

机构地区：[1]天津农学院动物科学与动物医学学院,天津300384

出　　处：《天津农学院学报》2020年第1期58-60,共3页Journal of Tianjin Agricultural University

基　　金：天津农学院大学生创新创业训练项目(201810061150)。

摘　　要：为研究黄芪多糖、灵芝多糖和转移因子3种免疫促进剂对犬瘟热免疫效果的影响,选择12只2月龄健康幼犬随机分为4组,试验A、B、C组分别给予转移因子、黄芪多糖和灵芝多糖,对照组给予等量生理盐水,定期采血并用(CDV-Ab)ELISA试剂盒测定犬瘟热抗体效价。结果表明:黄芪多糖和转移因子组均在第六天出现显著差异,但转移因子组的抗体效价一直高于黄芪多糖组,灵芝多糖组与对照组在第十天时抗体效价出现显著差异。说明3种免疫增效剂均对犬瘟热疫苗的免疫效果有明显的促进作用,临床上可酌情选用其中一种。The differences in immune efficiency to canine distemper(CD)among astragalus polysaccharide group,ganoderma polysaccharide group,transfer factor group and control group were studied.Twelve healthy young dogs aged 2 months post-injected with canine multi-kinds vaccine were randomly divided into four groups before bleeding for basic CDV antibody detection.Three experimental groups were administrated with transfer factor,astragalus polysaccharides and ganoderma polysaccharides,and the control group was given the same amount of physiological saline,then blood samples were taken on even-day for CDV Ab detection.The results showed that the antibody titers of the transfer factor group and the astragalus polysaccharide group were significantly different from those of the control on 6th day,and the antibody titers in transfer factor group were always higher than those of astragalus polysaccharide group.The antibody titers of the ganoderma polysaccharide group and control group were significantly different on the 10th day.Therefore,there are significant immuno efficiency in the three groups,which can be considered to be used in practice.

关 键 词：犬瘟热 免疫效果 转移因子 黄芪多糖 灵芝多糖 免疫促进剂 

分 类 号：S852.4[农业科学—基础兽医学]