在线凝胶渗透色谱-气相色谱/质谱法测定水中二异丙基萘、邻苯二甲酸二丁酯和邻苯二甲酸(2-乙基)己酯  

Determination of Di-isopropylnaphthalene,Dibutylphthalate and Bis(2-ethylhexyl)Phthalate in Water by Online Gel Chromatography-Gas Chromatography/Mass Spectrometry

作　　者：荣维广[1] 梁思慧 杨润[1] 吉文亮[1] 刘华良[1] 宋宁慧[3] RONG Weiguang;LIANG Sihui;YANG Run;JI Wenliang;LIU Hualiang;SONG Ninghui(Jiangsu Center for Disease Prevention and Control,Nanjing 210009;Department of Nutrition&Food Hygiene,School of Public Health,Southeast University,Nanjing 210009;Nanjing Institute of Environment Science,Department of Environmental Protection,Nanjing 210042)

机构地区：[1]江苏省疾病预防控制中心,江苏南京210009 [2]东南大学公共卫生学院,江苏南京210009 [3]环境保护部南京环境科学研究所,江苏南京210042

出　　处：《分析科学学报》2020年第2期250-254,共5页Journal of Analytical Science

基　　金：江苏省医学重点学科项目(No.ZDXKA2016008)。

摘　　要：建立了在线凝胶色谱-气相色谱/质谱法测定水中二异丙基萘、邻苯二甲酸二丁酯和邻苯二甲酸(2-乙基)己酯的方法。样品经正己烷液-液萃取,浓缩定容,经凝胶渗透色谱柱净化后,用DB-5MS色谱柱(25 m×0.25 mm,0.25μm)分离,质谱检测,内标法定量。在0.5μg/L、1.5μg/L和3.0μg/L 3个加标浓度下,3种目标物的平均回收率在95.45%~107.80%之间,相对标准偏差在2.64%~6.26%之间,3种目标物的方法检出限分别为0.01μg/L、0.5μg/L和0.5μg/L。该方法操作简单,分析成本低,适合水中二异丙基萘、邻苯二甲酸二丁酯、邻苯二甲酸(2-乙基)己酯的检测。Online gel chromatography-gas chromatography-mass spectrometry(GPC-GC/MS)was established to determinate di-isopropylnaphthalene(DIPN),dibutylphthalate(DBP)and bis(2-ethylhexyl)phthalate(DEHP)in water.After extracted by n-hexane,followed by clean-up treatment with online GPC and separated by DB-5 MS column,the identification and quantification were performed by GC/MS in selected ion monitoring(SIM)mode.The average recoveries of 3 compounds were in the range of 95.45%-107.80%,with the relative standard deviation in the range of 2.64%-6.26%spiked at 0.5μg/L,1.5μg/L and 3.0μg/L.The limits of detection of 3 compounds of this method were 0.01μg/L,0.5μg/L and 0.5μg/L respectively.The developed method is convenient,time-saving,environmental-friendly,accurate and sensitive,which is suitable for determination of DIPN DBP and DEHP.

关 键 词：在线凝胶色谱-气相色谱/质谱法 二异丙基萘 邻苯二甲酸二丁酯 邻苯二甲酸(2-乙基)己酯 水样 

分 类 号：O657.63[理学—分析化学]