睾丸菌群失调与非梗阻性无精症的研究进展  

Research progress of imbalance of testicular bacterial microbiome and non-obstructive azoospermia

作　　者：崔帆 阴克强 王文湛(综述)[1] 双卫兵(审校)[2] CUI Fan;YIN Keqiang;WANG Wenzhan;SHUANG Weibing(First Clinical Medical College,Shanxi Medical University,Taiyuan,Shanxi 030001,China;Department of Urology,the First Hospital of Shanxi Medical University,Taiyuan,Shanxi 030001,China)

机构地区：[1]山西医科大学第一临床医学院,山西太原030001 [2]山西医科大学第一医院泌尿外科,山西太原030001

出　　处：《中国医学工程》2019年第9期40-43,共4页China Medical Engineering

摘　　要：非梗阻性无精症是男性不育的主要病因之一,其发病机制较为复杂,且目前临床治疗乏善可陈。目前关于非梗阻性无精症的病因学研究主要集中于感染、免疫、内分泌因素及分子遗传学等方面。最近的研究提示睾丸菌群失调可能与非梗阻性无精症相关。因此,该文就正常睾丸组织菌群、非梗阻性无精症患者的睾丸组织菌群及其诊断、治疗等方面作一综述,以期为临床工作者提供参考。Non-obstructive azoospermia is one of the main causes of male infertility,its pathogenesis is more complicated and current clinical treatment is unsatisfactory.At present,the etiology of non-obstructive azoospermia mainly focuses on infection,immunity,endocrine factors and molecular genetics,etc.Recent studies suggest that imbalance of testicular bacterial microbiome may be related to non-obstructive azoospermia.Therefore,this article reviews the bacterial microbiome of normal testicular tissue,the testicular bacterial microbiome of patients with non-obstructive azoospermia and its diagnosis and therapy in order to provide reference for clinicians.

关 键 词：睾丸菌群 非梗阻性无精症 治疗 

分 类 号：R697.22[医药卫生—泌尿科学]