强直性脊柱炎湿邪致病病机与治法初探  

Discussion on pathogenesis and treatment of ankylosing spondylitis caused by dampness

作　　者：周东海 冯炯 王俏 温成平[1] ZHOU Dong-hai;FENG Jiong;WANG Qiao;WEN Cheng-ping(School of Basic Medical Science,Zhejiang Chinese Medical University,Hangzhou 310053,China)

机构地区：[1]浙江中医药大学基础医学院,杭州310053

出　　处：《中华中医药杂志》2020年第4期1814-1816,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家公益性行业专项(No.201507001-4)。

摘　　要：强直性脊柱炎为具有致畸性的难治性自身炎症性疾病,发病与环境和多基因遗传相关,治疗困难。本病中医多从补肾通瘀论治,但临床实践中体会到湿邪亦是重要致病因素。根据典籍湿气与湿邪论述并结合强直性脊柱炎现代病因、病理研究进展,认为湿邪是贯穿病程的重要致病因素。基于湿邪致病认识探讨了祛湿法在疾病不同阶段的具体运用,急性活动期解毒祛湿、通络止痛,慢性缓解期运脾祛湿、散瘀解毒,久病迁延期运脾益肾、通督祛湿。笔者认为在强直性脊柱炎治疗中应重视祛湿法的运用。Ankylosing spondylitis(AS)is a teratogenic refractory auto-inflammatory disease,which is associated with environmental and polygenic inheritance and is difficult to treat.Clinical practice found that dampness pathogen is also an important pathogenic factor,while common TCM therapeutic method is invigorating kidney for removing blood stasis.We presumed that dampness is an important pathogenic factor throughout the course of the disease according to the exposition of dampness qi and dampness pathogen in TCM classics,as well as the modern conception on etiology and pathology.Applications of‘eliminating dampness pathogen’method is illustrated by TCM formula used for AS in acute active phase,chronic remission and later period of the disease.In these periods,‘liminating dampness pathogen’method is flexibly applied in combination with removing toxicity for eliminating dampness pathogen,removing obstruction in collaterals and relieving pain,invigorating spleen for eliminating dampness,promoting blood circulation and detoxication,invigorating the spleen and invigorating the kidney,respectively.In authors’opinion,‘eliminating dampness pathogen’method should be paid more attention when using TCM remedy AS.

关 键 词：强直性脊柱炎 湿证 祛湿法 

分 类 号：R259[医药卫生—中西医结合]