内蒙古地区蒙古族与汉族多囊卵巢综合征痰湿证型患者临床特征对比研究  

Comparative study on clinical characteristics of obese polycystic ovary syndrome in Mongolian and Han women in Inner Mongolia based on phlegm-dampness syndrome of traditional Chinese medicine

作　　者：张锁[1] 师建平[1] 乌日古木拉 赵敏[1] 李志茹[1] 陈春[1] ZHANG Suo;SHI Jian-ping;WU Rigumula;ZHAO Min;LI Zhi-ru;CHEN Chun(Inner Mongolia Medical University,Hohhot 010010,China;Inner Mongolia Autonomous Region Maternal and Child Health Hospital,Hohhot 010020,China)

机构地区：[1]内蒙古医科大学,呼和浩特010010 [2]内蒙古自治区妇幼保健院,呼和浩特010020

出　　处：《中华中医药杂志》2020年第4期2143-2145,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：内蒙古自治区卫生计生科研项目(No.201702062);内蒙古医科大学人才团队建设项目(No.NYTD-2017009)。

摘　　要：目的:探索研究内蒙古地区属于中医痰湿证型的蒙古族与汉族多囊卵巢综合征(PCOS)患者临床特征之间的差异。方法:收集符合纳入标准的蒙古族PCOS患者103例,汉族PCOS患者97例,分别填写问卷调查表,行超声检查,内分泌相关激素测定及血脂测定,将数据使用SPSS 22.0进行统计分析。结果:汉族与蒙古族PCOS患者在平均年龄、初潮年龄、平均经期天数、体质量指数、腰臀比及平均子宫内膜厚度方面无显著差异;汉族PCOS患者痤疮发生率显著高于蒙古族PCOS患者(P<0.05)。汉族与蒙古族PCOS患者右侧及左侧卵巢体积大小比较无显著差异。汉族与蒙古族PCOS患者雌二醇、卵泡刺激素(FSH)、黄体生成素(LH)、LH/FSH值比较无显著差异。蒙古族PCOS患者睾酮(T)值显著高于汉族患者(P<0.05)。汉族与蒙古族PCOS患者空腹胰岛素、空腹血糖、胰岛素抵抗指数平均值比较无显著差异,蒙古族PCOS患者总胆固醇(TC)、甘油三脂(TG)均显著高于汉族PCOS患者(P<0.05)。结论:内蒙古地区蒙古族与汉族属痰湿证型的PCOS患者之间比较,蒙古族PCOS患者在痤疮发生率、继发性闭经发生率、T及TG、TC含量方面均与汉族PCOS患者存在明显差异,可能与蒙古族特定的种族特点及相关基因有关。Objective:To explore and study the difference of clinical characteristics between Mongolian and Han women in phlegm-dampness syndrome with polycystic ovary syndrome(PCOS)in Inner Mongolia.Methods:A total of 103 cases of Mongolian PCOS patients and 97 cases of Han PCOS patients were collected.Questionnaires were filled out,ultrasonography,endocrine-related hormones and blood lipids were measured,and the data was analyzed by SPSS 22.0.Results:There were no significant differences in average age,menarche age,average menstrual days,BMI,WHR and average endometrial thickness between Han and Mongolian patients,and the incidence of acne in Han patients was significantly higher than that in Mongolian patients(P<0.05).There was no significant difference in the size of right and left ovaries between Han and Mongolian patients.There was no significant difference in E2,FSH,LH and LH/FSH between Han and Mongolian patients.The testosterone level of Mongolian patients was significantly higher than that of Han patients(P<0.05).There was no significant difference in FINS,FBG and HOMA-IR between Han and Mongolian patients.The TG and TC of Mongolian patients were higher than those of Han patients(P<0.05).Conclusion:There are significant differences in the incidence of acne,delayed amenorrhea,testosterone,TG and TC between Mongolian and Han patients with polycystic ovary syndrome of phlegm-dampness syndrome in Inner Mongolia,which may be related to the specific ethnic characteristics and related genes of Mongolian.

关 键 词：痰湿证 蒙古族 汉族 多囊卵巢综合征 临床特征 

分 类 号：R271.9[医药卫生—中西医结合]