微小RNA早期诊断急性肾损伤的研究进展  

MicroRNA as an early diagnosis biomarker of acute kidney injury

作　　者：李湘玉(综述) 李瑛(审校)[1] LI Xiangyu;LI Ying(Department of Nephrology,Key Laboratory of Kidney Disease and Blood Purification in Hunan,The Second Xiangya Hospital of Central South University,Changsha 410007,China)

机构地区：[1]中南大学湘雅二医院肾脏科,长沙410007

出　　处：《肾脏病与透析肾移植杂志》2020年第2期160-164,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

基　　金：国家自然科学基金面上项目(81370792);长沙市卫计局基础研究项目(K91901122)。

摘　　要：急性肾损伤(AKI)是由多种病因引起的短时间内肾功能急剧恶化的临床综合征,由于血清肌酐值和尿量变化在早期诊断AKI和评判预后等方面存在不足,因此寻找并获得有潜力的AKI生物标志物是亟待解决的临床实际问题。Acute kidney injury(AKI)is a clinical syndrome of sharp deterioration of renal function in short period of time caused by a variety of etiologies.Due to the low efficiency of serum creatinine value and urine volume changes in early diagnosis of AKI,searching for potential AKI biomarkers is an urgent clinical problem to be solved.In this paper,research progress of microRNA as biomarker in the early diagnosis of acute kidney injury is reviewed.

关 键 词：急性肾损伤 微小RNA 早期诊断 

分 类 号：R69[医药卫生—泌尿科学]