氨甲环酸结合引流管夹闭对初次单侧THA失血量的影响  

Influences of Blood Loss between Tranexamic Acid Combined with Drainage Tube Clamping on Primary Unilateral THA

作　　者：高小强[1] 陈宣煌[1] 林海滨[1] 郑祖高[1] 郑锋[1] 吴长福[1] GAO Xiaoqiang;CHEN Xuanhuang;LIN Haibin;ZHENG Zugao;ZHENG Feng;WU Changfu(Department of Orthopedics,The Affiliated Hospital of Putian University,Putian Fujian 351100,China)

机构地区：[1]莆田学院附属医院骨科,福建莆田351100

出　　处：《莆田学院学报》2020年第2期44-47,共4页Journal of putian University

基　　金：福建省自然科学基金资助项目(2018J01194);福建省临床重点专科建设项目(2018145);莆田市科技局科研创新专项项目(2019SZP01);莆田市临床重点专科建设项目(2016228)。

摘　　要：探讨静脉滴注氨甲环酸结合引流管夹闭对初次单侧全髋关节置换(THA)失血量的影响。随机将50例拟行初次单侧人工THA的股骨头坏死患者分成观察组和对照组。观察组在切开皮肤之前30 min静脉滴注氨甲环酸100 mL(1 g/100 mL),术后夹闭引流管6 h;对照组仅夹闭引流管6 h,未滴注氨甲环酸。对比两组术后24 h引流量、24/72 h血红蛋白指标、输血人数、术后两周及两个月髋关节Harris评分,观察组均优于对照组(P<0.05)。结果表明,静脉滴注氨甲环酸结合引流管夹闭可明显降低初次人工单侧THA患者术后引流量及失血量,降低输血率,值得临床推广。The influence of closure of drainage tube was investigated after tranexamic acid intravenous injection on blood loss in patients through total hip arthroplastry(THA).Fifty patients with femoral head necrosis who underwent initial unilateral THA were randomly assigned to the observation group and the control group.The observation group was intravenously instilled with 100 mL,1.0 g of tranexamic acid injection 30 min before the incision,and the drainage tube was closed for 6 h after the drainage tube.The control group only clamped the drainage tube for 6 h,uninjected tranexamic acid.The drainage volume at 24 h after operation was compared between the two groups,24/72 h hemoglobin index,blood transfusion number,and two-week and two-month hip(Harris)scores.The observation group was superior to the control group(P<0.05).Intravenous infusion of tranexamic acid combined with drainage tube clamping can significantly reduce postoperative drainage and blood loss in patients with primary THA,reduce blood transfusion rate,which is worth clinical promotion.

关 键 词：全髋关节置换 氨甲环酸 引流管 引流量 失血量 

分 类 号：R687.4[医药卫生—骨科学]