不同剂量丙戊酸钠防治小儿复杂性热性惊厥的效果分析  

Effects of Different Doses of Sodium Valproate on the Prevention and Treatment of Complex Febrile Convulsions in Children

作　　者：林东 连文昌[1] 郑立娴 LIN Dong;LIAN Wenchang;ZHENG Lixian(Pediatrics Department,The Affiliated Hospital of Putian University,Putian Fujian 351100,China)

机构地区：[1]莆田学院附属医院儿科,福建莆田351100

出　　处：《莆田学院学报》2020年第2期53-56,共4页Journal of putian University

摘　　要：为分析不同剂量丙戊酸钠防治小儿复杂性热性惊厥的效果,选取莆田学院附属医院儿科2017年1月—2018年1月收治的116例复杂性热性惊厥患儿,随机分为观察组和对照组,每组58例。对照组行常规标准剂量丙戊酸钠防治,观察组行小剂量丙戊酸钠防治。对比两组患儿治疗有效率、不良反应发生率、复发数、惊厥控制时间和住院时间。结果显示,观察组患儿治疗有效率较高,不良反应发生率较低且复发数较少,惊厥控制时间和住院时间较短,与对照组相比,差异具有统计学意义(P<0.05)。结果表明,小剂量丙戊酸钠防治小儿复杂性热性惊厥的效果较为理想,治疗有效率高,复发问题得到改善,患儿不良反应少,且康复时间短。The effect of different doses of sodium valproate on prevention and treatment of complicated febrile convulsion in children was analyzed.116 children with complicated febrile convulsion admitted to our hospital from January 2017 to January 2018 were randomly divided into observation group and control group,with 58 cases in each group.The control group was treated with high-dose sodium valproate and the observation group with low-dose sodium valproate.The effective rate of treatment,incidence of adverse reactions,number of recurrence,time of disappearance of clinical symptoms and length of stay were compared between the two groups.Compared with the control group,the observation group had higher effective rate of treatment,lower incidence of adverse reactions,fewer recurrence,shorter time of disappearance of clinical symptoms and shorter hospital stay(P<0.05).The result showed that low-dose sodium valproate is effective in preventing and treating complicated febrile convulsion in children,with high effective rate,improved recurrence,less adverse reactions and short recovery time.

关 键 词：丙戊酸钠 复杂性热性惊厥 住院时间 不良反应 

分 类 号：R720.597[医药卫生—急诊医学] R725.9[医药卫生—儿科]