磺胺甲恶唑在二硫化钼纳米片修饰电极上的电化学行为  

Electrochemical behavior of sulfamethoxazole on molybdenum disulfide nanosheet modified electrode

作　　者：金诗瑶 佟曦媛 鄂义峰 JIN Shiyao;TONG Xiyuan;E Yifeng(College of Pharmacy,Jinzhou Medical University,Jinzhou 121000)

机构地区：[1]锦州医科大学药学院,锦州121000

出　　处：《分析试验室》2020年第4期422-426,共5页Chinese Journal of Analysis Laboratory

基　　金：辽宁省自然基金项目(2015010717-301)资助。

摘　　要：采用了研磨后超声和离心分离方法制备了二硫化钼纳米片,通过原子力显微镜(AFM)和扫描电子显微镜(SEM)对不同离心速度分离的二硫化钼纳米片进行了表征。使用循环伏安法(CV)和差分脉冲伏安法(DPV)在磺胺甲恶唑溶液中对二硫化钼纳米片修饰的玻碳电极进行了电化学行为研究。结果显示,磺胺甲恶唑在二硫化钼修饰电极的循环伏安图上有一对氧化还原峰。其峰电流值与扫描速度的平方根成正比,是扩散控制过程。DPV扫描结果显示,磺胺甲恶唑的峰电流与其浓度之间存在着明显的线性关系。研磨超声方法制备出的二硫化钼纳米片层材料在电极上能够加速电子的转移和传输,从而有效提高峰电流值,为进一步研制准确测定磺胺甲恶唑电化学传感器提供了一种可选择的材料和电化学分析方法。Molybdenum disulfide nanosheet was prepared by ultrasonic and centrifugal separation after grinding.The atomic force microscopy(AFM)and scanning electron microscopy(SEM)were used to characterize surface topography of themolybdenum disulfide nanosheets separated at different centrifugal speeds.Cyclic voltammetry(CV)and differential pulse voltammetry(DPV)were used to study the electrochemical behavior of molybdenum disulfide nanosheet modified glassy carbon electrode in sulfamethoxazole solution.The results showed that there was a pair of redox peaks on the cyclic voltammogram of sulfamethoxazole at the molybdenum disulfide modified electrode.The peak current was proportional to the square root of the scanning speed,which was a diffusioncontrolled process.The result of DPV showed that there was a linear relationship between the peak current of sulfamethoxazole and its concentration.The results showed that the molybdenum disulfide nanosheet material prepared by grinding ultrasonic method can accelerate the transfer and transmission of electrons on the electrode,thus effectively increasing the peak current,which provides a suitable method and materials for the further development of the electrochemical sensor related to the determination of sulfamethoxazole.

关 键 词：电化学传感器 二硫化钼纳米片 修饰电极 磺胺甲恶唑 

分 类 号：R917[医药卫生—药物分析学]