基于加权逼近理想解排序法人血白蛋白注射液药物利用评价  

Evaluation of rational use of human serum albumin injection based on weighted TOPSIS method

作　　者：翟宇瑶[1] 段万里[2] 向俊西[3] 薛小荣[1] ZHAI Yuyai;DUAN Wanli;XIANG Junxi;XUE Xiaorong(Department of Pharmacy,Xi’an Forth Hospital,Xi’an,Shaanxi 710004,China;Department of Urology,The People’s Hospital of Shaanxi Province,Xi’an,Shaanxi 710068,China;Department of Hepatobiliary Surgery,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an,Shaanxi 710061,China)

机构地区：[1]西安市第四医院药剂科,陕西西安710004 [2]陕西省人民医院泌尿外科,陕西西安710068 [3]西安交通大学第一附属医院肝胆外科,陕西西安710061

出　　处：《安徽医药》2020年第6期1254-1257,共4页Anhui Medical and Pharmaceutical Journal

基　　金：国家自然科学基金(81501608)。

摘　　要：目的探讨基于加权逼近理想解排序法(TOPSIS法)人血白蛋白注射液评价标准建立的方法。方法创建人血白蛋白注射液合理性应用点评细则,采用属性层次分析法加权计算评价指标的相对权重,并运用TOPSIS的数据处理方法评价各病历医嘱与完全合理医嘱的距离即其相对接近程度系数Ci,计算合理医嘱的比例,以评价用药合理性。对西安市第四医院2018年1—12月336例住院使用人血白蛋白的医嘱进行合理性分析。结果336例病例中相对接近程度系数Ci最高的为1.0,最低的0.3,18.75%(63/336)为合理,72.92%(245/336)为基本合理(0.6≤Ci<0.8),8.33%(28/336)为不合理(Ci<0.6)。结论基于加权TOPSIS法建立与实施人血白蛋白点评较为科学,该院人血白蛋白注射液临床应用较为合理。Objective To explore the method of evaluating the drug utilization of human serum albumin(HSA)injection based on weighted technique for order preference by similarity to an ideal solution(TOPSIS)method.Methods Human serum albumin evaluation index and evaluation criteria were established.The relative weight of evaluation index was calculated by using attribute-based AHM weight method,and the relative proximity coefficient Ci between medical orders and complete rational ones was evaluated by using TOPSIS processing method.The proportion of rational medical orders was calculated to evaluate the rationality of drug use.The rationality of 336 inpatients with human serum albumin(HSA)in Xi’an Forth Hospital from June to December 2018 was analyzed.Results Among 336 medical records which used human serum albumin,the highest value of the relative proximity coefficient Ci was 1.0,and the lowest value of the relative proximity coefficient Ci was 0.3.72.92%(245/336)was reasonable(0.6≤Ci<0.8)and 8.33%(28/336)was unreasonable(Ci<0.6).Conclusion Establishment and implementation of human serum albumin evaluation based on weighted TOPSIS method is scientific,and the clinical application of human serum albumin injection in this hospital is reasonable.

关 键 词：血清白蛋白/投药和剂量 处方不当 药物利用评审 加权逼近理想解排序法(TOPSIS法) 

分 类 号：R977.6[医药卫生—药品]