惠州地区2型糖尿病住院患者非酒精性脂肪肝患病情况的调查  

Investigation of Nonalcoholic Fatty Liver Disease in Hospitalized Patients with Type 2 Diabetes in Huizhou Area

作　　者：骆秀婷[1] 林克宣[2] 陈利强[1] LUO Xiuting;LIN Kexuan;CHEN Liqiang(Huizhou First Hospital,Huizhou 516001,China;不详)

机构地区：[1]广东省惠州市第一人民医院,广东惠州516001 [2]广东省惠州市中心人民医院

出　　处：《中国医学创新》2020年第14期125-128,共4页Medical Innovation of China

基　　金：2018年惠州市科研立项课题(180604091742842)。

摘　　要：目的:调查惠州地区2型糖尿病住院患者合并非酒精性脂肪肝(NAFLD)的患病率及危险因素。方法:选取2018年7月-2019年6月于惠州市第一人民医院及惠州市中心人民医院内分泌科住院的2型糖尿病患者1 070例。按是否合并NAFLD分为病例组(n=579)与对照组(n=491)。比较两组临床特征,分析2型糖尿病合并NAFLD的危险因素。结果:2型糖尿病合并NAFLD患病率为54.11%(579/1 070)。两组年龄、性别、体重指数(BMI)、糖化血红蛋白、尿酸及甘油三酯比较,差异均有统计学意义(P<0.05)。BMI、甘油三酯及尿酸为2型糖尿病合并NAFLD的危险因素(P<0.05)。结论:惠州地区2型糖尿病患者合并NAFLD患病率达54.11%,女性发生率较高;BMI、甘油三酯及尿酸是2型糖尿病患者合并NAFLD的危险因素。Objective:To investigate the prevalence and risk factors of type 2 diabetic inpatients with nonalcoholic fatty liver disease (NAFLD) in Huizhou area.Method:A total of 1 070 patients with type 2 diabetes hospitalized in endocrinology department of Huizhou First Hospital and Huizhou Central People’s Hospital from July 2018 to June 2019 were selected.They were divided into case group (n=579) and control group (n=491) according to whether combination of NAFLD.Clinical characteristics of the two groups were compared and risk factors for type 2 diabetes mellitus with NAFLD were analyzed.Result:There were statistically significant differences in age,sex,body mass index (BMI),glycosylated hemoglobin,uric acid and triglyceride between the two groups (P<0.05).BMI,triglyceride and uric acid were risk factors for type 2 diabetes mellitus with NAFLD (P<0.05).Conclusion:The prevalence of nonalcoholic fatty liver disease in type 2 diabetes in Huizhou area is 54.11%,and the incidence is higher in women;BMI,triglyceride and uric acid are risk factors for NAFLD in patients with type 2 diabetes.

关 键 词：惠州地区 2型糖尿病 非酒精性脂肪肝 

分 类 号：R587.1[医药卫生—内分泌] R575.5[医药卫生—内科学]