新生儿窒息后酸中毒与多脏器功能损伤相关性分析  

Correlation Analysis between Acidosis and Multi-organ Functional Injury after Neonatal Asphyxia

作　　者：林广玉 杨婕 邓秋敏 叶小霞 李晓兰 LIN Guangyu;YANG Jie;DENG Qiumin;YE Xiaoxia;LI Xiaolan(Dianbai District People’s Hospital of Maoming,Maoming 525400,China;不详)

机构地区：[1]广东省茂名市电白区人民医院,广东茂名525400

出　　处：《中国医学创新》2020年第15期34-37,共4页Medical Innovation of China

基　　金：茂名市科技计划项目(190411211702723)。

摘　　要：目的:分析新生儿窒息后酸中毒与多脏器功能损伤的相关性,旨在获得指向性的指标为复苏后治疗提供有效指导。方法:选取2016年1月-2020年2月本院新生儿科收治的84例新生儿窒息患儿。比较不同pH、BE值患儿脏器损伤情况;分析pH、BE值与脏器损伤的相关性。结果:pH与BE值越低,患儿脏器损伤、重度脏器损伤数目及死亡例数越高(P<0.05),其中pH<6.95、BE<-25 mmol/L时,患儿死亡率最高。新生儿窒息后pH、BE值与患儿脏器损伤、重度脏器损伤数目及死亡例数均呈负相关(P<0.05)。结论:新生儿窒息后酸中毒程度与多脏器功能损伤密切相关,影响患儿的预后。酸中毒越严重,脏器损伤数目越多,其中pH<6.95、BE<-25 mmol/L时提示患儿死亡率最高,预后极差。Objective:To analyze the correlation between acidosis and multi-organ functional injury after neonatal asphyxia,in order to obtain directional indicators to provide effective guidance for post-resuscitation treatment.Method:A total of 84 cases of neonatal asphyxia admitted to the department of neonatology in our hospital from January 2016 to February 2020 were selected.The organ damage of children with different pH value and BE value were compared.The correlation between pH,BE value and organ damage was analyzed.Result:The lower the pH and BE value,the higher the number of organ injury,severe organ injury and death cases(P<0.05).When pH<6.95 and BE<-25 mmol/L,the mortality rate was highest.After neonatal asphyxia,pH and BE were negatively correlated with the number of organ injuries,severe organ injuries and death cases(P<0.05).Conclusion:The degree of acidosis after neonatal asphyxia is closely related to the multi-organ functional injury,which affects the prognosis of children.The more severe the acidosis,the more the number of organ injuries.When pH<6.95 and BE<-25 mmol/L,the mortality rate is the highest and the prognosis is extremely poor.

关 键 词：新生儿窒息 酸中毒 多脏器功能损伤 

分 类 号：R722.12[医药卫生—儿科]