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作 者:付阳阳[1] 龚利[1] 姜淑云[1] 李建华[1] 张昊[1] 邵盛[1] 储宇舟[1] 陈浩 何鹏飞[1] 杨成浩 梁红广 FU Yang-yang;GONG Li;JIANG Shu-yun;LI Jian-hua;ZHANG Hao;SHAO Sheng;CHU Yu-zhou;CHEN Hao;HE Peng-fei;YANG Cheng-hao;LIANG Hong-guang(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)
机构地区:[1]上海中医药大学附属岳阳中西医结合医院,上海200437
出 处:《中医药导报》2020年第8期32-34,44,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy
基 金:国家自然科学基金面上项目(81373763)。
摘 要:目的:探索影响坐位调膝法治疗膝骨关节炎(knee osteoarthritis,KOA)即刻临床疗效的相关因素。方法:纳入205例采用坐位调膝法治疗的KOA患者,采用SPSS 21.0软件对可能影响该法疗效的10个相关因素进行单因素分析及多因素Logistic回归分析。结果:单因素分析显示,体质指数(BMI)、疼痛程度、日常活动程度、影像学K-L分级不同水平之间临床有效率比较,差异有统计学意义(P<0.05);Logistic回归分析显示,与轻度疼痛比较,疼痛程度为中度或重度的KOA患者疗效较好[OR=5.54,95%CI(1.44,21.34);OR=7.62,95%CI(1.46,39.86)];与日常活动程度为轻度比较,日常活动程度为中度或重度的KOA患者疗效较好[OR=13.21,95%CI(3.26,53.61);OR=13.48,95%CI(2.42,75.01)];与在影像学分级0级比较,Ⅳ级患者的疗效差[OR=0.10,95%CI(0.01,0.77)]。结论:日常活动程度、疼痛程度及K-L分级是影响坐位调膝法治疗KOA疗效的因素。疼痛程度越严重,日常活动程度越差,K-L分级越低,坐位调膝法治疗KOA疗效越好。Objective: To explore the factors affecting the treatment of knee osteoarthritis by statistical analysis of the factors related to the immediate clinical efficacy of knee osteoarthritis(KOA). Methods: A total of205 patients with knee osteoarthritis were enrolled in the study. The results of single factor analysis and multivariate logistic regression analysis were performed using SPSS 21.0 software for ten related factors that may affect the efficacy of the method. Results: Univariate analysis showed that there was a statistically significant difference in the clinical effective rate between body mass index(BMI), pain level, daily activity level, and imaging K-L grade(P<0.05). Logistic regression analysis showed that compared with mild pain, KOA patients with moderate or severe pain had better efficacy [OR=5.54, 95%CI(1.44, 21.34);OR=7.62, 95%CI(1.46,39.86)]. Compared with the mild degree of daily activity, the patients with moderate or severe degree of daily activity had better curative effect [OR=13.21, 95% CI(3.26,53.61);OR=13.48, 95%CI(2.42,75.01)]. Compared with imaging grade 0,the effect of grade Ⅳ patients was poor [OR=0.10, 95%CI(0.01,0.77)]. Conclusion: The degree of daily activities,pain and KL grading are factors influencing the efficacy of sitting-position knee-adjusting therapy for KOA. The more severe the pain, the worse the level of daily activities,and the lower the K-L classification, the better the effect of sitting knee adjustment on KOA.
分 类 号:R246.9[医药卫生—针灸推拿学]
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