酸性功能性离子液体催化合成二甘醇二苯甲酸酯  

Acidic functional ionic liquid catalyzed synthesis of diethylene glycol dibenzoate

作　　者：王莹 曹震 薛誉 胡燚[1] WANG Ying;CAO Zhen;XUE Yu;HU Yi(School of Pharmaceutical Sciences,Nanjing Tech University,Nanjing 211800,China)

机构地区：[1]南京工业大学药学院,江苏南京211800

出　　处：《生物加工过程》2020年第3期277-282,共6页Chinese Journal of Bioprocess Engineering

基　　金：江苏高校“青蓝工程”,国家自然科学基金面上项目(21676143)。

摘　　要：选用6种酸性功能化离子液体作为催化剂,催化苯甲酸和二甘醇酯化合成增塑剂二甘醇二苯甲酸酯(DEDB),通过实验考察反应温度、时间、催化剂种类及用量、原料投料比等工艺因素对合成收率的影响,确定了最佳反应条件:优选1丁基磺酸3甲基咪唑对甲基苯磺酸盐([(CH 2)4 SO 3 HMIm]TS)为催化剂,反应温度160℃,时间4.0 h,苯甲酸与二甘醇的摩尔比为2.2∶1,催化剂用量为二甘醇质量的10%,最终发现DEDB产率可达99.1%,且产品具有较高的品质。产物可以通过简单倾倒与离子液体催化剂分离,离子液体具有优异的重复使用性,使用10次后DEDB的产率仍有95.2%。Six acid functional ionic liquids were selected as catalysts for the esterification of benzoic acid and diethylene glycol to synthesize plasticizer diethylene glycol dibenzoate(DEDB).The effects of reaction temperature,reaction time,amount of catalyst and raw materials ratio on the synthesis of DEBD were investigated.Under the optimized conditions:1-butylsulfonic acid-3-methylimidazole ptoluene sulfo nate([(CH 2)4 SO 3 HMIm]TS)as catalyst with 10%of the mass of diethylene glycol,reaction temperature 160℃,reaction time 4.0 h,the molar ratio of n(benzoic acid)to n(diethylene glycol)2.2∶1,the yield of DEDB could reach 99.1%with high quality.The product can be separated from ionic liquid by simple decantation.Ionic liquid catalyst had excellent reusability,and the yield of DEDB could be obtained in 95.2%even after 10 times of recycling.

关 键 词：离子液体 二甘醇二苯甲酸酯 增塑剂 酯化反应 

分 类 号：TQ414[化学工程]