“邵氏五针法”为主治疗变应性鼻炎-哮喘综合征:多中心随机对照研究  

"SHAO’s five-needle method" as the main treatment for allergic rhinitis and asthma syndrome: a multi-center randomized controlled trial

作　　者：郑洁 邵素菊[1,2] 王培育[1,2] 秦小永 王庆波[4] 张晓刚[1,2] 任重[2] 张君[1,2] 华金双[1,2] 邵伯雍 张聪聪 ZHENG Jie;SHAO Su-ju;WANG Pei-yu;QIN Xiao-yong;WANG Qing-bo;ZHANG Xiao-gang;REN Zhong;ZHANG Jun;HUA Jin-shuang;SHAO Bo-yong;ZHANG Cong-cong(College of Acupuncture-Moxibustion and Tuina,Henan University of CM,Zhengzhou 450008,China;Department of Acupuncture and Moxibustion,Third Affiliated Hospital of Henan University of CM,Zhengzhou 450008,China;Department of Acupuncture and Moxibustion,Kaifeng Hospital of TCM;Department of Acupuncture and Moxibustion,First Affiliated Hospital of Henan University of CM)

机构地区：[1]河南中医药大学针灸推拿学院,郑州450008 [2]河南中医药大学第三附属医院针灸科,郑州450008 [3]开封市中医院针灸科 [4]河南中医药大学第一附属医院针灸科

出　　处：《中国针灸》2020年第5期483-487,共5页Chinese Acupuncture & Moxibustion

基　　金：河南省科技厅重点科技攻关项目:142102310283;国家中医药管理局全国中医学术流派传承工作室第二轮建设项目:国中医药人教函[2019]62号;河南省中医药科学研究专项项目:2015ZY02056。

摘　　要：目的:比较"邵氏五针法"为主与常规取穴针刺治疗变应性鼻炎-哮喘综合征的临床疗效。方法:将210例变应性鼻炎-哮喘综合征患者随机分为观察组(105例,脱落4例)和对照组(105例,脱落4例)。观察组采用"邵氏五针法"为主治疗,穴取肺俞、大椎、风门、印堂、上迎香、合谷等;对照组行常规针刺治疗,穴取肺俞、中府、太渊、定喘、膻中、印堂、风门、足三里等。两组均每天治疗1次,每周6次,共治疗4周。观察两组患者治疗前后及治疗后第1、2、3个月随访时症状体征评分;检测两组患者治疗前后肺功能第1秒用力呼气容积(FEV1)、呼气峰值流速(PEF)及外周血嗜酸性粒细胞计数,比较治疗后两组临床疗效。结果:观察组总有效率为98.0%(99/101),优于对照组的94.1%(95/101,P<0.01)。治疗1、2、3、4周后,两组患者症状体征总分均较治疗前明显降低(P<0.01);治疗后及随访各时间点,观察组症状体征总分均低于对照组(P<0.01);与治疗4周后比较,观察组各随访时点症状体征总分比较差异均无统计学意义(P>0.05),对照组第3个月随访时症状体征总分明显升高(P<0.05)。两组患者治疗后肺功能FEV1、PEF较治疗前升高(P<0.01),外周血嗜酸性粒细胞计数较治疗前降低(P<0.01),观察组改善幅度大于对照组(P<0.01,P<0.05)。结论:"邵氏五针法"为主治疗变应性鼻炎-哮喘综合征可改善患者的临床症状体征和肺功能,降低外周血嗜酸性粒细胞计数,疗效优于常规取穴针刺。Objective To compare the clinical effect differences between "SHAO ’s five-needle method" and routine acupoint selection on allergic rhinitis and asthma syndrome. Methods A total of 210 patients with allergic rhinitis and asthma syndrome were randomly divided into an observation group(105 cases, 4 cases dropped off) and a control group(105 cases,4 cases dropped off). The patients in the observation group were treated with "SHAO ’s five-needling method", and the acupoints of Feishu(BL 13), Dazhui(GV 14), Fengmen(BL 12), Yintang(GV 29), Shangyingxiang(EX-HN 8) and Hegu(LI 4), etc. were selected;the patients in the control group was treated with routine acupuncture, and the acupoints of Feishu(BL 13), Zhongfu(LU 1), Taiyuan(LU 9), Dingchuan(EX-B 1), Danzhong(CV 17), Yintang(GV 29), Fengmen(BL 12) and Zusanli(ST 36), etc.were selected. The treatment in the two groups was given once a day, 6 times a week, for 4 weeks. The score of symptoms and signs was observed before and after treatment as well as 1 month, 2 months and 3 months after treatment. The forced expiratory volume in 1 second(FEV1), peak expiratory flow(PEF) and eosinophils in peripheral blood were measured before and after treatment in the two groups. After treatment, the clinical therapeutic effect was compared between the two groups.Results The total effective rate was 98.0%(99/101) in the observation group, which was superior to 94.1%(95/101) in the control group(P<0.01). Compared before treatment, the total score of symptoms and signs in the two groups was significantly decreased at 1, 2, 3 and 4 weeks of treatment(P<0.01);after treatment and at each time point of follow-up, the total score of symptoms and signs in the observation group was lower than that in the control group(P<0.01). Compared with 4 weeks of treatment, the total score of symptoms and signs at each time point of follow-up was not statistically different in the observation group(P>0.05), and the total score of symptoms and signs in the third month of follow-up in the control group

关 键 词：变应性鼻炎-哮喘综合征 针刺疗法 邵氏五针法 随机对照试验 

分 类 号：R246.1[医药卫生—针灸推拿学]