N-甲基丙烯酰基-N'-芳酰氨基硫脲的合成与除草活性研究  

Synthesis and Herbicidal Activity of N-methacryloyl-N’-aroyl Thiosemicarbazides

作　　者：郑广进[1] 蔡杰慧 张海全[1] Zheng Guangjin;Cai Jiehui;Zhang Haiquan(Guangxi Colleges and Universities Key Laboratory Breeding Base of Chemistry of Guangxi Southwest Plant Resources,Guangxi Normal University for Nationalities,Chongzuo 532200,China)

机构地区：[1]广西民族师范学院广西高校桂西南特色植物资源化学重点实验室培育基地,广西崇左532200

出　　处：《山东化工》2020年第8期1-2,6,共3页Shandong Chemical Industry

基　　金：广西民族师范学院校级科研项目(2016YB030)。

摘　　要：为寻求具有除草活性的农药先导化合物,以取代苯甲酸为原料经酯化、肼解、加成反应合成了5个酰氨基硫脲类化合物,其结构经1H NMR确证。初步的除草活性测试结果表明,所合成的化合物在100 mg/L下对鬼针草根和反枝苋根具有较好的抑制作用,抑制率分别达到70%和80%以上。In order to search for novel pesticide lead compounds with herbicidal activity,five acyl thiosemicarbazides were synthesized from substituted benzoic acid via esterification,hydrazinolysis and addition reactions.The structures of as-synthesized were characterized by 1H NMR.The preliminary herbicidal activity test indicated that the compounds synthesized have good herbicidal activity against the root of Bidens pilosa L and Amaranthus retroflexus L at the concentration of 100 mg/L,which the inhibition rate were up to 70%and 80%,respectively.

关 键 词：酰氨基硫脲 合成 除草活性 

分 类 号：O626.2[理学—有机化学]