Highly Stereoselective Direct Construction of Diaryl-Substituted Cyclobutanes  

作　　者：Xiang-Yang Song Liu-Peng Zhao Lijia Wang Yong Tang 

机构地区：[1]State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,University of Chinese Academy of Sciences,345 Lingling Lu,Shanghai 200032,China [2]Shanghai Key Laboratory of Green Chemistry and Chemical Processes,Department of Chemistry,East China Normal University,3663 North Zhongshan Road,Shanghai 200062,China

出　　处：《Chinese Journal of Chemistry》2020年第3期259-262,共4页中国化学（英文版）

基　　金：We thank the NSFC(Nos.21432011,21772224);the CAS(Nos.QYZDY-SSW-SLH016,XDB20000000,2017301);the STCSM(Nos.17JC1401200,17ZR1436900)for the financial support.We also thank Dr.Xue-Bing Leng(SIOC)for X-ray crystal analysis.

摘　　要：A copper catalyzed stereoselective[2+2]cyclization has been developed,providing a concise protocol to the direct construction of diaryl-substituted cyclobutanes in up to 99%yield with up to>95/5 dr.Meanwhile,the enantioselective version of this reaction has also been achieved,leading to a series of optically active diaryl-substituted cyclobutanes with up to 94%ee.

关 键 词：SUBSTITUTED BUTANE HIGHLY 

分 类 号：O62[理学—有机化学]